Protein Alignment slpr and Matk

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_038935769.1
• Gene: Matk / 60450
• RGDID: 69058
• Length: 496
• Species: Rattus norvegicus
• Alignment Length: 466
• Identity: 108/466 - (23%)
• Similarity: 171/466 - (36%)
• Gaps: 163/466 - (34%)

  Fly    61 ELTLRRGEIVVV---------------------------------LSTDSEVSGDVGWWTGKIGD 92
            ||..|:|::|.:                                 ||||.::| .:.|:.|||..
  Rat    25 ELAFRKGDMVTILEACEDKSWYRAKHHSSGQEGLLAAAALRQREALSTDPKLS-LMPWFHGKISG 88

  Fly    93 KV----------GVF--------PKDFVT----DEDPLQLNVSSAIGDIQPHE------------ 123
            :.          |:|        |.|:|.    ..|.:...|....|.:...|
  Rat    89 QEAIQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTIDEAVCFCNLMDMVE 153

  Fly   124 -----------------------------------IEYNELDIKEVIGSGGFCKVHRGYYDGEEV 153
                                               ::...|.:...||.|.|..|.:|.|.|::|
  Rat   154 HYTRDKGAICTKLVKPKRKQGAKSAEEELAKAGWLLDLQHLTLGAQIGEGEFGAVLQGEYLGQKV 218

  Fly   154 AIK-----IAHQTGEDDMQRMRDNVLQEAKLFWALKHENIAALRGVCLNTKLCLVMEYARGGSLN 213
            |:|     :..|.           .|.|..:...|:|.|:..|.||.|:..|.:|||:...|:|.
  Rat   219 AVKNIKCDVTAQA-----------FLDETAVMTKLQHRNLVRLLGVILHHGLYIVMEHVSKGNLV 272

  Fly   214 RILAGK----IPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLK 274
            ..|..:    :....|:.:|:.:|.||.||.::   .::||||.:.|:|:.|.:        ..|
  Rat   273 NFLRTRGRALVSTSQLLQFALHVAEGMEYLESK---KLVHRDLAARNILVSEDL--------VAK 326

  Fly   275 ITDFGLAREMYNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELIT-GETPYKGFDPL 338
            ::|||||:........|:.....|..||.:....:|..|||||:||||||:.: |..||......
  Rat   327 VSDFGLAKAELRKGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMVSS 391

  Fly   339 SVAYGVAVNTLT--------LP--------------------IPKTCPETWGALMKSCWQTDPHK 375
            :.......:.:|        ||                    .|.:||.....||.|||:.:|.:
  Rat   392 TPGRAACASRVTDCPHPCYPLPPYLQSLKEVSEAVEKGYRMEPPDSCPGPVHTLMGSCWEAEPSR 456

  Fly   376 RPGFKEILKQL 386
            ||.|::|:::|
  Rat   457 RPPFRKIVEKL 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	19/97 (20%)
		STKc_MLK	134..389	CDD:270963	84/291 (29%)
Matk	XP_038935769.1	SH3	9..67	CDD:473055	5/41 (12%)
		SH2_csk_like	77..174	CDD:198190	14/97 (14%)
		Protein Kinases, catalytic domain	187..470	CDD:473864	85/303 (28%)