Protein Alignment slpr and si:ch211-45c16.2

DIOPT Version :9

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_017213349.1
• Gene: si:ch211-45c16.2 / 568412
• ZFINID: ZDB-GENE-081105-15
• Length: 982
• Species: Danio rerio
• Alignment Length: 1085
• Identity: 291/1085 - (26%)
• Similarity: 422/1085 - (38%)
• Gaps: 298/1085 - (27%)

  Fly    22 LHHPQIPEIPIPDLEQVETQVGDGSLWTALYDYDA--QGEDE---LTLRRGEIVVVLSTDSEVSG 81
            |||.|   :|:.|    |...|.....|||.:...  ||..|   |.|:..|       |:|..|
Zfish    80 LHHLQ---LPVRD----EEPGGTSPPCTALSEDSTREQGHFENSVLQLQEQE-------DAETPG 130

  Fly    82 DVGWWTGKIG------DKVGVFPKDFVTDE------DPLQLNVSSA-----------IGDIQP-- 121
            ..|  .|..|      ::....|.:...|:      |.::|:...|           .|.::|
Zfish   131 SCG--QGGCGSGGEEKNEENGCPMEHSGDDTHHHPHDDIKLHFHRAGTGSGGFLEGLFGCLRPVW 193

  Fly   122 --------------HEIEYNELDIKEV-----IGSGGFCKVHRGYYDGEEVAIKIAHQTGEDDMQ 167
                          .::|..|:..:|:     :|||....|..|.:..||||||...:..|.|::
Zfish   194 NIIGKTYSTEYKLQQQVEMWEVPFEEISELQWLGSGAQGAVFLGKFRSEEVAIKKVREQKETDIK 258

  Fly   168 RMRDNVLQEAKLFWALKHENIAALRGVCLNTK-LCLVMEYARGGSLNRIL-AG-KIPPDVLVNWA 229
            .:|           .|||.||.:.:|||.... .|::|||...|.|..:| || ||.|.:||:||
Zfish   259 HLR-----------KLKHPNIISFKGVCTQAPCYCIIMEYCAQGQLYEVLRAGRKITPCLLVDWA 312

  Fly   230 IQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYN-TQRMSAA 293
            ..||.||||||..   .||||||||.|||:        .|..::||:|||.::|:.: :.:||.|
Zfish   313 SGIASGMNYLHLH---KIIHRDLKSPNVLV--------TQNDSVKISDFGTSKELSDKSTKMSFA 366

  Fly   294 GTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCP 358
            ||.|||.||||.....|:..|:||:||:||||:|||.|||..|..::.:||..|:|.||:|.|||
Zfish   367 GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCP 431

  Fly   359 ETWGALMKSCWQTDPHKRPGFKEILKQLESIACSKFTLTPQESFHYMQECWRKEIAGVLHDLREK 423
            :.:..|||..||..|..||.|::||..|: ||.:....||||::...|..||:|:
Zfish   432 DGFKILMKQTWQGKPRNRPSFRQILLHLD-IASADVLGTPQETYFKCQTEWREEV---------- 485

  Fly   424 EKRFQTIEEE---LRNKEEQLLRVQNEQREKANLLKIREQNLRERER---VLIERELVMLQPVPS 482
            :|.|:.|:.|   :...:|:|:|.:.::...|  |.|||...|:.||   :.:|...:|||  ..
Zfish   486 KKHFEKIKSEGTCIHRLDEELIRRRRDELRHA--LDIREHYERKLERANNLYMELSAIMLQ--LE 546

  Fly   483 KRKHKKGKKNKPLQISLP-TGFRHTI-TAVRDKA-----------------EQP---------GS 519
            .|:.:..|:.:.::...| |..||.: ..||..|                 :||         |.
Zfish   547 VREKELLKREQAVEKKYPGTYKRHLVRPIVRPNAVEKLIKKKSSMNHKPGTQQPKRPDLLRSDGI 611

  Fly   520 PSFSGLRIVALTDGH------KGKT-WGPSTMHQRERSLLPSQLSGGQPEWPAQTSTHSSFSKSA 577
            ||...|...:...|.      .||| :.....|:|..|      .|...|:|.....:|    ..
Zfish   612 PSVEPLPAPSPLSGSPKVSTPPGKTRYRSKPRHRRANS------KGSHNEFPGVLKPNS----GP 666

  Fly   578 PNLDKKQQQQNQQQVASLTPPPGLGILGGSGGAGGTPATPLLYPGIPIILTRPNNNNIGNCKAIT 642
            |...:..|:||..|...|.||..                       |:..||.|        |:.
Zfish   667 PEEQQPLQEQNYLQNHPLPPPEP-----------------------PLAKTREN--------AVA 700

  Fly   643 TTITTTTTTTTNNNNNNNNSISANNNNQLNNISTINSNNNNN-QTNLT-SQPNTIIVLQNGRNNS 705
            |                    .|||.......:.:.|...:: |..|: |.|:.|....:..:..
Zfish   701 T--------------------CANNLRYFGPAAALRSPQTDHLQRRLSGSSPDLISTAVDADSRL 745

  Fly   706 NSSTTSQSPAKIYHRARSQEYGLDHPLAYQPPPLYLVTDDSSETDTVASPTGCFHFLKSGNSSAA 770
            ..|:....||.:....::      ||.                       .||.|..::..:.:.
Zfish   746 RRSSIPPGPAPLCPCCQA------HPF-----------------------PGCKHCQQTPAAPSH 781

  Fly   771 SGAVHLHRFGGSLGNSPAVGRKKHSLDSSSHHPPANGSNSFALPNQL-TL----------PSEDN 824
            ....|......:.|..||   .|.:|:     |.|.|.:....|..| ||          ..|:.
Zfish   782 PQLPHYSLLSTNDGTPPA---SKRNLE-----PTAEGQDKEEKPALLHTLRPLRKTGDESSEEEE 838

  Fly   825 NTYDH--AFYRDVIKKMSMASSERVNSKSSGDLTMYNSSTPLTARDCDDAEEAFEGGRFQRNFSG 887
            ...|.  .|.|.......|:|.:..::.||.:|::            .|.|   ||.....:.||
Zfish   839 GEVDSEVEFPRRQRPHRCMSSFQSYSTFSSENLSV------------SDGE---EGNTSDHSHSG 888

  Fly   888 SQFPRHCFFTRQEEEGEAEDE-----DAVAAEVDT-ADADADDECQVPASQMRQNSTTSRKSSVT 946
               |.......|||.   .||     ..:..::.| :|..:|.||.|     |:..|......:.
Zfish   889 ---PLEQLSGSQEEH---LDELLSHTPEIPIDISTQSDGLSDKECAV-----RRVKTQISLGKLC 942

  Fly   947 FQSVSFEEPDFVATPRTTARSDLYTSSASISFATYRSASPSLSSS 991
            ....|:|.|.....      ||..||.|..|.||.|:..|...||
Zfish   943 ADEHSYENPLHFGD------SDCDTSDAECSDATIRNKPPGAPSS 981

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	16/67 (24%)
		TyrKc	129..386	CDD:197581	115/265 (43%)
		STKc_MLK	134..389	CDD:270963	115/263 (44%)
si:ch211-45c16.2	XP_017213349.1	STKc_MAP3K12_13	226..462	CDD:270961	115/258 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X88
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010