DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slpr and map3k7

DIOPT Version :9

Sequence 1:	NP_001188558.1	Gene:	slpr / 44111	FlyBaseID:	FBgn0030018	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	XP_009292938.1	Gene:	map3k7 / 553788	ZFINID:	ZDB-GENE-041001-135	Length:	578	Species:	Danio rerio

Alignment Length:	269	Identity:	98/269 - (36%)
Similarity:	146/269 - (54%)	Gaps:	23/269 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 EIEYNELDIKEVIGSGGFCKVHRGYYDGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKHEN 187
            ||:|.:::::||:|.|.|..|.:..:.|.:||||......|      ::..:.|.:....:.|.|
Zfish    19 EIDYVDIEVEEVVGRGAFGVVCKAKWKGRDVAIKTIESESE------KNAFIVELRQLSRVDHPN 77

  Fly   188 IAALRGVCLNTKLCLVMEYARGGSLNRILAGKIP-----PDVLVNWAIQIARGMNYLHNEAPMSI 247
            |..|.|.| |..:|||||||.||||..:|.|..|     ....::|.:|.::|::|||...|.::
Zfish    78 IVKLYGSC-NNPVCLVMEYAEGGSLYNVLHGAEPLPHYTASHAMSWCLQCSQGVSYLHGMKPKAL 141

  Fly   248 IHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSAAGTYAWMPPEVISVSTYSKF 312
            ||||||..|:|:   :.|.    ..|||.|||.|.:: .|...:..|:.|||.|||...|.||:.
Zfish   142 IHRDLKPPNLLL---VAGG----TVLKICDFGTACDI-QTHMTNNKGSAAWMAPEVFEGSNYSEK 198

  Fly   313 SDVWSYGVLLWELITGETPYK--GFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHK 375
            .||:|:|::|||:||...|:.  |.....:.:.|...|.. |:.|..|:...:||..||..||.:
Zfish   199 CDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHRGTRP-PLIKNLPKAIESLMTRCWSKDPSQ 262

  Fly   376 RPGFKEILK 384
            ||..:||:|
Zfish   263 RPSMEEIVK 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		TyrKc	129..386	CDD:197581	95/263 (36%)
		STKc_MLK	134..389	CDD:270963	94/258 (36%)
map3k7	XP_009292938.1	TyrKc	25..273	CDD:197581	95/263 (36%)
map3k7	XP_009292938.1	STKc_TAK1	31..281	CDD:270960	93/257 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D346131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920