DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slpr and Pbk

DIOPT Version :9

Sequence 1:	NP_001188558.1	Gene:	slpr / 44111	FlyBaseID:	FBgn0030018	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_075698.1	Gene:	Pbk / 52033	MGIID:	1289156	Length:	330	Species:	Mus musculus

Alignment Length:	276	Identity:	71/276 - (25%)
Similarity:	107/276 - (38%)	Gaps:	79/276 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 DDMQR--MRDNVLQEAKLFWALKHENIAALRGV--CLNTKLCLVMEYARGGSLNRIL-------A 217
            ||..|  .:..:..|||:...|.|.||...|..  ..:..|||.|||....|||.::       .
Mouse    70 DDHYRTVYQKRLTDEAKILKNLNHPNIIGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERNKDSG 134

  Fly   218 GKIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAR 282
            ...|..|::..|:.:|||:.|||.|  ..::|.|:|||||:|....|       |:||.|.|::.
Mouse   135 SPFPAAVILRVALHMARGLKYLHQE--KKLLHGDIKSSNVVIKGDFE-------TIKICDVGVSL 190

  Fly   283 EMYNTQRMSAA-------GTYAWMPPEVISVS-TYSKFSDVWSYGVLLWELIT------------ 327
            .:  .:.|:..       ||..|.|.|.:..: ..:..:||:::|:.|||::|
Mouse   191 PL--DENMTVTDPEACYIGTEPWKPKEALEENGIITDKADVFAFGLTLWEMMTLCIPHVNLPDDD 253

  Fly   328 ---------------------GETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQT 371
                                 |..|....:.|..:|..|:.                |...|...
Mouse   254 VDEDATFDESDFDDEAYYAALGTRPSINMEELDDSYQKAIE----------------LFCVCTNE 302

  Fly   372 DPHKRPGFKEILKQLE 387
            ||..||....|::.||
Mouse   303 DPKDRPSAAHIVEALE 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		TyrKc	129..386	CDD:197581	69/273 (25%)
		STKc_MLK	134..389	CDD:270963	71/276 (26%)
Pbk	NP_075698.1	PKc_TOPK	31..318	CDD:270903	69/274 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810