Protein Alignment slpr and zap70

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_001006825.1
• Gene: zap70 / 448557
• XenbaseID: XB-GENE-956409
• Length: 609
• Species: Xenopus tropicalis
• Alignment Length: 312
• Identity: 100/312 - (32%)
• Similarity: 145/312 - (46%)
• Gaps: 41/312 - (13%)

  Fly    95 GVFPKDFVTDEDPLQLNVS---SAIGDIQPHEIEYNELDIK-------EV-IGSGGFCKVHRGYY 148
            |..|:.|:.....|.::.|   |...|  |.|::..:|.:|       || :|||.|..|.:|.|
 Frog   283 GYTPEPFIGKSRILPMDTSVYESPYSD--PEELKERKLFVKRELLLIDEVELGSGNFGCVKKGVY 345

  Fly   149 DGE----EVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKHENIAALRGVCLNTKLCLVMEYARG 209
            ..:    :||||:..   ..|.:.:||.:::||::...|.:..|..:.|||....|.||||.|.|
 Frog   346 KLKKRQIDVAIKVLK---VQDEKNVRDEMMKEAEIMHQLDNPYIVRMIGVCEAENLMLVMEMASG 407

  Fly   210 GSLNRILAGK---IPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQK 271
            |.||:.|..|   ||...:|....|::.||.||..:   :.:||||.:.|||:        :.|.
 Frog   408 GPLNKFLGAKKDVIPMSNIVELMHQVSIGMKYLEGK---NFVHRDLAARNVLM--------VNQH 461

  Fly   272 TLKITDFGLAR-----EMYNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELIT-GET 330
            ..||:||||::     :.|...:........|..||.|:...:|..|||||||:.:||..| |:.
 Frog   462 YAKISDFGLSKALAADDSYYKAKSFGKWPLKWYAPECINYRKFSSRSDVWSYGITMWEAFTYGQK 526

  Fly   331 PYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEI 382
            |||......|...:..|. .|..|..||.....:|..||......||.|..:
 Frog   527 PYKKLKGTEVMSFIERNE-RLACPAGCPPEMYQVMLDCWIFKMEDRPNFDNV 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	3/8 (38%)
		STKc_MLK	134..389	CDD:270963	88/263 (33%)
zap70	NP_001006825.1	SH2_N-SH2_Zap70_Syk_like	8..111	CDD:198191
		SH2_C-SH2_Zap70	152..256	CDD:198265
		Protein Kinases, catalytic domain	321..589	CDD:473864	90/272 (33%)