Protein Alignment slpr and MOS

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_005363.1
• Gene: MOS / 4342
• HGNCID: 7199
• Length: 346
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 78/342 - (22%)
• Similarity: 148/342 - (43%)
• Gaps: 86/342 - (25%)

  Fly   107 PLQLNVSSAIGDIQPH-----------EIEYNELDIKEVIGSGGFCKVHRGYYDGEEVAIKIAHQ 160
            |.:|.....:|...|.           .|::.::.:.:.:|:|||..|::..|.|..||||
Human    27 PSELPAKLLLGATLPRAPRLPRRLAWCSIDWEQVCLLQRLGAGGFGSVYKATYRGVPVAIK---- 87

  Fly   161 TGEDDMQRMRDNVLQEAKLFWA------LKHENIAALRGVCLNTKL--------CLVMEYARGGS 211
                .:.:...|.|...:.|||      |:|:||  :|.|..:|:.        .::||:....:
Human    88 ----QVNKCTKNRLASRRSFWAELNVARLRHDNI--VRVVAASTRTPAGSNSLGTIIMEFGGNVT 146

  Fly   212 LNRIL------------------AGKIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVL 258
            |::::                  .|::.....:.:::.:..|:.:||::   ||:|.|||.:|:|
Human   147 LHQVIYGAAGHPEGDAGEPHCRTGGQLSLGKCLKYSLDVVNGLLFLHSQ---SIVHLDLKPANIL 208

  Fly   259 IYEAIEGNHLQQKTLKITDFGLAREM-----YNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSY 318
            |.|        |...||:|||.:.::     :.|......|||....||::.....:..:|::|:
Human   209 ISE--------QDVCKISDFGCSEKLEDLLCFQTPSYPLGGTYTHRAPELLKGEGVTPKADIYSF 265

  Fly   319 GVLLWELITGETPYKGFDPLSVAYGVAVNTL-----------TLPIPKTCPETWGALMKSCWQTD 372
            .:.||::.|.:.||.| :...:.|.|....|           :||     .:..|.:::.||:..
Human   266 AITLWQMTTKQAPYSG-ERQHILYAVVAYDLRPSLSAAVFEDSLP-----GQRLGDVIQRCWRPS 324

  Fly   373 PHKRPGFKEILKQLESI 389
            ..:||..:.:|..|.|:
Human   325 AAQRPSARLLLVDLTSL 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		STKc_MLK	134..389	CDD:270963	72/302 (24%)
MOS	NP_005363.1	STKc_Mos	56..338	CDD:270881	71/308 (23%)