Protein Alignment slpr and cdi

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_524401.2
• Gene: cdi / 42289
• FlyBaseID: FBgn0004876
• Length: 1213
• Species: Drosophila melanogaster
• Alignment Length: 1354
• Identity: 270/1354 - (19%)
• Similarity: 459/1354 - (33%)
• Gaps: 384/1354 - (28%)

  Fly    19 LEQLHHPQIP-EIPIPDLEQVETQVGDGSLWTALYDYDAQGEDELTLRRGEIVVVLSTDSEVSGD 82
            |.|...|..| ||....::||::......:|.:............|...|:.........:...:
  Fly     3 LNQHSGPGPPSEICGLSVDQVDSSAASPFIWPSTAGMCTTATTVTTSTNGDATAEAPVKHQPLHN 67

  Fly    83 VGWWTGKIGDKVGVFPKDFVTDEDPLQLNVS-----SAIGDIQPHEIEYNELD-IKEVIGSGGFC 141
            .||    ||:.:...|.......|.|....|     :|:..:      |:..| :||.||||.|.
  Fly    68 GGW----IGNGLPPAPVTRTISSDRLVTGSSCRALRTAVSAL------YSVDDFVKEKIGSGFFS 122

  Fly   142 KVHRGYYDGEEVAIKIAHQ-TGE------DDMQRMRDNVLQEAKLFWALKHENIAALRGVCLNT- 198
            :|:           |:.|: ||:      :.::..|.|:|:|.:|...|.|.||.:..|||:..
  Fly   123 EVY-----------KVTHRTTGQVMVLKMNQLRANRPNMLREVQLLNKLSHANILSFMGVCVQEG 176

  Fly   199 KLCLVMEYARGGSLNRILAGK---IPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLI- 259
            :|..:.||..||||.::||.|   :.....:..|:.|||||:|:|:   ..|.||||.|.||||
  Fly   177 QLHALTEYINGGSLEQLLANKEVVLSATQKIRLALGIARGMSYVHD---AGIFHRDLTSKNVLIR 238

  Fly   260 ------YEAIEGNHLQQKTLKITDFGLAREM---YNTQRMSAAGTYAWMPPEVISVSTYSKFSDV 315
                  |||:.|           |||||.::   ....|:...|:..|:.||.:....|.:.|||
  Fly   239 NLANDQYEAVVG-----------DFGLAAKIPVKSRKSRLETVGSPYWVSPECLKGQWYDQTSDV 292

  Fly   316 WSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFK 380
            :|:|::..|:|..........|.:.::|:.........|...|..:..|...|...|...||.|.
  Fly   293 FSFGIIQCEIIARIEADPDMMPRTASFGLDYLAFVELCPMDTPPVFLRLAFYCCLYDAKSRPTFH 357

  Fly   381 EILKQ---------------------LESIACS-------KFTLTPQESF--------------- 402
            :..|:                     ||.|.||       ..||||:.|.
  Fly   358 DATKKLTLLLEKYEHESSAGASPLSSLELINCSPGGSDSENVTLTPRASVPTVATICTAPAGTLT 422

  Fly   403 -HYMQEC--------WRKEIAGVL---------------HDLREKEKR-FQTIEEEL----RNKE 438
             .::||.        .:|..:..|               |.|:.:.:| .|.:|.|:    |:..
  Fly   423 PRHLQEVDEDGFRFPSKKSASAALPGTPNGSAGSSGFDDHILKSRVRRATQKLEAEILLHRRSLS 487

  Fly   439 EQLLR--VQNEQREKANLLKIREQNLRERE----------------------------RVLIERE 473
            |.::.  :.....:||...:::.|......                            .||..|:
  Fly   488 ENIIHFPMHTSPSDKARCHQMQRQRSSTHSPTPPRQLSSVQLPATSIPDPPPLPKPVPAVLTLRK 552

  Fly   474 LVMLQPVPSKRKHKKGKKNKPLQ-ISLPTGFRHTITAVRDKAEQPG------------SPSFSGL 525
            :...|..|:..|...|.|..|.: ::...|.:..:.| ..|....|            :|.|..|
  Fly   553 VGDPQYKPTSEKDHNGSKPNPFEALAQLRGVKKILDA-NPKTYAAGVGDLFSSCFEMLAPFFKEL 616

  Fly   526 RIVALTDGHKGKTWGPSTMHQRERSLLPSQLSGGQPEWPAQ--TSTHSSFSKSAPNLDKKQQQQN 588
            ..:....|.:|  .|.||    |.:...::.|...|..|..  .|.|.:...||..|...|:..|
  Fly   617 AAMQSKAGAQG--GGTST----EETSTGNKASAATPSEPKSLPVSPHMTRKYSAIELRLPQRISN 675

  Fly   589 QQQVASLTPPPGLGILGGSGGAGGTPATPLLYPGIPIILTRPNNNNIGNCKAITTTITTTTTTTT 653
            ....|..:.||                        |.|....:.::..:|           .:..
  Fly   676 AAPPAVTSAPP------------------------PSIALPTDEDDCDDC-----------NSEG 705

  Fly   654 NNNNNNNNSISANNNNQLNNI--STINSNNNNNQTNLTSQPNTIIVLQNGRNNSNSSTTSQSPAK 716
            .:.:...|...|.:::..:.:  ||:.:.......:|.:.|     |..|.|.::..:||..
  Fly   706 EDPDGGGNCADAESSSDDSAVRPSTVPTARKYRANSLYAHP-----LFRGSNGTSMKSTSTG--- 762

  Fly   717 IYHRARSQEYGLDHPLAYQPPPLYLVTDDSSETDTVASPTG----CFHFLKSGNSS---AASGAV 774
                            .::.|.|...   |:.|.|:.:..|    |....:|...|   |:|||
  Fly   763 ----------------EFESPTLLKA---SASTITLTASVGATNSCEDLTESARKSKEQASSGA- 807

  Fly   775 HLHRFGGSLGNSPAVGRKKHSLDSSSHHPPANGSNSFALPNQLTLPS-------EDNNTYDHAFY 832
                       :.||    .:|.:     |.:|.::..:...:::.|       |..||.|....
  Fly   808 -----------TAAV----QALPT-----PMSGCSTRLVETPVSVSSCTDLELDELKNTCDLNEL 852

  Fly   833 RDVIKKMSMASS-ERVNSKSSGDLTMYNSSTPLTARDCDDAEEAFEGGRFQRNFS---------- 886
            ::..:::.:.:: .|.:|..||..:.:|          ::::.|.....|.|..:
  Fly   853 KNSCEQLPLKTNLTRRDSIESGFFSCFN----------EESDAAITNNSFGRQLNGIGSLGFGCG 907

  Fly   887 GSQFPRHCFFTRQEEE--------GEAEDEDAVAA-----EVDTADADADDECQVPASQMRQ--- 935
            |.....:|.:.:.:.:        .::|..|.:|:     ...|:.::|.......|:|.:|
  Fly   908 GGGNSSNCCYEKLKTQLMLDACVSADSEINDKLASLCRCCYYATSTSNAAVTAAAAAAQQQQQSH 972

  Fly   936 --NSTTSRKSSV-------------TFQSVSFE-----EPDFVATPRTTARSDLYTSSASISFAT 980
              |.|:|..|||             |..|.:.:     :.|.||:.||..|.  ||...::
  Fly   973 LLNDTSSTSSSVLLIDNDPAVIGGNTSSSTALDSMDDLDADIVASRRTHQRR--YTCHHAL---- 1031

  Fly   981 YRSASPSLSSSSTTASASPSIASTEAVNGYHMQE----NSILNTRRMQD---VQPHPDVIKLRAQ 1038
             .|.:.|.|..:.|||....:|....::....:.    |.:|..:....   .....|:..|...
  Fly  1032 -LSGNGSESQMAATASLINRLALDSEIHTLLQRSPFATNQLLYCKNRTSSIYTDSSDDISSLAGS 1095

  Fly  1039 EQRQQTKNQKKQRPKHITKSKSVEAPVEGQHHEHDDHNDPQHQHHSAGSSKIRALF-------NL 1096
            :............|.  |:|..:...||....:..| :.|...||..|:..:.|..       |.
  Fly  1096 DSLLWDDRSFTALPS--TRSAQIAKIVEYFERKRQD-SSPPSVHHRNGNGTVAAAVAASALGSNY 1157

  Fly  1097 FTRSRKKYSKLAEHNMVGGPEFCAIDPYQTDLAMGGSSRSLKRKGKKPQTQSCE 1150
            .:...::||....|                 |...|....|.:|..:.:...||
  Fly  1158 LSYESRRYSDFKRH-----------------LNADGLCFDLDKKPAQQRMMVCE 1194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	8/56 (14%)
		STKc_MLK	134..389	CDD:270963	85/296 (29%)
cdi	NP_524401.2	Protein Kinases, catalytic domain	116..370	CDD:473864	83/278 (30%)