DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slpr and LOC405768

DIOPT Version :9

Sequence 1:	NP_001188558.1	Gene:	slpr / 44111	FlyBaseID:	FBgn0030018	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_001353900.1	Gene:	LOC405768 / 405768	-ID:	-	Length:	477	Species:	Danio rerio

Alignment Length:	348	Identity:	121/348 - (34%)
Similarity:	182/348 - (52%)	Gaps:	49/348 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 EIEYNELDIKEVIGSGGFCKVHRGYY--DGEEVAIKIAHQTGEDDMQRMRDNVLQ---EAKLFWA 182
            :|.::::...|..|.|.|..|:|.::  ..:|||:|               .:|:   ||::...
Zfish    41 QIPFDDIRFYENCGGGSFGSVYRAHWVPQDKEVAVK---------------KLLKIDAEAEILSV 90

  Fly   183 LKHENIAALRGVCLNT-KLCLVMEYARGGSLNRILAG----KIPPDVLVNWAIQIARGMNYLHNE 242
            |.|:||....|..|.. ...:|.|||..|||...|:.    ::..|.::.||::||:||:|||.|
Zfish    91 LSHKNIIQFYGAILEAPNYGIVTEYASRGSLYEYLSSADSEEMDMDQVMTWAMEIAKGMHYLHAE 155

  Fly   243 APMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSAAGTYAWMPPEVISVS 307
            ||:.:|||||||.||::        .....|||.|||.::.:.:|..||..||:.||.||||...
Zfish   156 APLKVIHRDLKSRNVVL--------TADNVLKICDFGASKMVSHTTHMSLVGTFPWMAPEVIQSL 212

  Fly   308 TYSKFSDVWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTD 372
            ..|:..|.:||||:|||::|.|.|:|||:.|.||:.|........||.:||.::..||:.||..:
Zfish   213 PVSETCDTYSYGVVLWEMLTREVPFKGFEGLQVAWLVVEKHERPTIPSSCPASFADLMRRCWNAE 277

  Fly   373 PHKRPGFKEILKQLESI--------ACSKFTLTPQESFHYMQECWRKEIAGVLHDLREKEKRFQT 429
            |.:||.||:||..||::        .|:.|       .|...| ||.||...|..|::.|:....
Zfish   278 PKERPQFKQILSTLETMKNDSKLPDQCNSF-------LHNKAE-WRCEIEETLERLKQLERELSC 334

  Fly   430 IEEELRNKEEQLLRVQNEQREKA 452
            .|:||..:|.:|...:|...|::
Zfish   335 KEQELEERERRLTEWENRLMERS 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		TyrKc	129..386	CDD:197581	100/266 (38%)
		STKc_MLK	134..389	CDD:270963	101/264 (38%)
LOC405768	NP_001353900.1	STKc_MLTK	53..294	CDD:270962	101/263 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D346131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910