Protein Alignment slpr and ripk2

DIOPT Version :9

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_919392.2
• Gene: ripk2 / 373874
• ZFINID: ZDB-GENE-030902-3
• Length: 584
• Species: Danio rerio
• Alignment Length: 509
• Identity: 128/509 - (25%)
• Similarity: 212/509 - (41%)
• Gaps: 134/509 - (26%)

  Fly   124 IEYNELDIKEVIGSGGFCKVHRGYYDG--EEVAI---KIAHQTGEDDMQRMRDNVLQEAKLFWAL 183
            |.|.:|.....|..|||..|.|..:..  ..|||   |:....||    |.|:.:|:||::....
Zfish    23 IPYRKLTDLHYISKGGFGTVFRAQHSDWRTTVAIKCLKLDSPVGE----RERNCLLKEAEVLHKA 83

  Fly   184 KHENIAALRGVCLNTK-LCLVMEYARGGSLNRILAGK-IPPDVLVNWAI------QIARGMNYLH 240
            :..:|..:.|||...: .|::.||...|||:.:|..| |.|  .|.|.:      :||.|:|:||
Zfish    84 RFNHIIQIFGVCNEPEFFCIITEYMTNGSLDELLHEKDIYP--AVAWPLRLRILYEIALGVNFLH 146

  Fly   241 NEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLA--REMYNTQRMSA-----AGTYAW 298
            |.:| .::|.|||:.|:|    ::|.:    .:||.||||:  |::..|:...:     .||..:
Zfish   147 NMSP-PLLHHDLKTQNIL----MDGEY----HVKIADFGLSKWRQLSITKGSGSKPAEMGGTVIY 202

  Fly   299 MPPEVISVS----TYSKFSDVWSYGVLLWELITGETPY-KGFDPLSVAYGV--------AVNTLT 350
            ||||....|    |..|: |::||.:::||:::...|: :..:|:.:.:.|        .:::|.
Zfish   203 MPPEEYEPSKTRRTDVKY-DMYSYAIIMWEVLSRRIPFEEATNPMQIMFSVLRGARPDTGLDSLP 266

  Fly   351 LPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIACSKFTLTPQESFHYMQECWRKEIAG 415
            :.||..  ||...||.|.|..:|.:||.|...|.:||.:.
Zfish   267 VDIPSR--ETLINLMTSGWTANPDERPSFLHCLIELEPML------------------------- 304

  Fly   416 VLHDLREKEKRFQTIEEELRNKEEQLLRVQN-EQREKANLLKIREQNLRERERVLIERELVMLQP 479
                     :||..|:     ..|.:|.|:. :.|..::.....:.|.::.|...: :||.:..|
Zfish   305 ---------RRFDEID-----VLEAVLEVKRIKYRRPSSCCSSTQSNGKKIEEKCV-KELNVPWP 354

  Fly   480 VPSKRKHKKGKKNKPLQISLPTGFRHTITAVRDKAEQPGSPSFSGLRIVALTDGHKGKTWGPSTM 544
            ..|.........::..:||.| ||. ||:.       |...:::||               ||
Zfish   355 DNSSTSGSGSCSSQEAEISQP-GFL-TIST-------PSQGAYAGL---------------PS-- 393

  Fly   545 HQRERSLLPSQLSGGQPEWPAQTSTHSSFSKSAPNLDKKQQQQNQQQVASLTPP 598
                 ||:...|...:|          .....:|| :...:.|..|.|:.|..|
Zfish   394 -----SLMSLPLDPPKP----------LMDNCSPN-NLSPEYQTAQVVSDLNIP 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		TyrKc	129..386	CDD:197581	88/289 (30%)
		STKc_MLK	134..389	CDD:270963	89/287 (31%)
ripk2	NP_919392.2	STKc_RIP2	30..313	CDD:270928	92/339 (27%)
		S_TKc	34..297	CDD:214567	86/280 (31%)
		CARD_RIP2_CARD3	471..557	CDD:176764

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100013
Panther	1	1.100	-	-	O	PTHR44329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910