DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slpr and pbk

DIOPT Version :9

Sequence 1:	NP_001188558.1	Gene:	slpr / 44111	FlyBaseID:	FBgn0030018	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_001002387.1	Gene:	pbk / 360218	ZFINID:	ZDB-GENE-030523-2	Length:	339	Species:	Danio rerio

Alignment Length:	277	Identity:	73/277 - (26%)
Similarity:	119/277 - (42%)	Gaps:	64/277 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 KIAHQTGEDDMQRMRDNVLQEAKLFWALKHENIAALRG--VCLNTKLCLVMEYARGGSLNRILAG 218
            ||..:..:..:...:..:.:|||:...|||.||...|.  ...:...||.||:....|||.::..
Zfish    68 KINSKCAQGQVSVYQKRLCEEAKILKDLKHPNIVGFRAFTTAKDGSKCLAMEFGGEQSLNDLIEK 132

  Fly   219 K-------IPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKIT 276
            :       .|.|.:...|:.:|||:.|||||  ..::|.|:||.||:|....|       ::||.
Zfish   133 RREEGLQAFPVDTIEKVALHVARGLLYLHNE--KKLLHGDMKSCNVVIKGDFE-------SIKIC 188

  Fly   277 DFGLAREMYNTQRMS-----AAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPY---- 332
            |.|::..:....::|     ..||..|.|.|.:.....:..:|:::||:.|||::|...|:
Zfish   189 DVGVSLPLDENMQVSDPKAHYIGTEPWKPKEALEDGVITDKADIFAYGLTLWEMMTLSVPHLEML 253

  Fly   333 --------------KGFDPLSVAY------GVAVNTLTLPIPKTCPETWGALMKS------CWQT 371
                          :.||  ..||      ..|::.:||         .|:..:.      |.:.
Zfish   254 DTEGDEDDDDESFEEDFD--EDAYYERLGSRPALDAVTL---------GGSYQRMVELFCLCTEE 307

  Fly   372 DPHKRPGFKEILKQLES 388
            ||.|||....|::.|||
Zfish   308 DPQKRPSAAHIVQVLES 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		TyrKc	129..386	CDD:197581	70/273 (26%)
		STKc_MLK	134..389	CDD:270963	73/277 (26%)
pbk	NP_001002387.1	PKc_TOPK	36..325	CDD:270903	73/277 (26%)
pbk	NP_001002387.1	Pkinase_Tyr	38..322	CDD:285015	70/273 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810