Protein Alignment slpr and Map3k20

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_001385922.1
• Gene: Map3k20 / 311743
• RGDID: 1561394
• Length: 802
• Species: Rattus norvegicus
• Alignment Length: 863
• Identity: 220/863 - (25%)
• Similarity: 351/863 - (40%)
• Gaps: 170/863 - (19%)

  Fly   123 EIEYNELDIKEVIGSGGFCKVHRGYY--DGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKH 185
            :|::::|...|..|.|.|..|:|..:  ..:|||:|...:            :.:||::...|.|
  Rat    10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLK------------IEKEAEILSVLSH 62

  Fly   186 ENIAALRGVCLN-TKLCLVMEYARGGSL----NRILAGKIPPDVLVNWAIQIARGMNYLHNEAPM 245
            .|:....||.|. ....:|.|||..|||    |...:.::..:.::.||..:|:||:|||.|||:
  Rat    63 RNVIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMEHIMTWATDVAKGMHYLHMEAPV 127

  Fly   246 SIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSAAGTYAWMPPEVISVSTYS 310
            .:|||||||.||:|  |.:|      .|||.|||.:|...:|..||..||:.||.||||.....|
  Rat   128 KVIHRDLKSRNVVI--AADG------VLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQSLPVS 184

  Fly   311 KFSDVWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHK 375
            :..|.:||||:|||::|.|.|:||.:.|.||:.|......|.||.:||.::..|:..||:.|..|
  Rat   185 ETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKK 249

  Fly   376 RPGFKEILKQLESIACSKFTLTPQE--SFHYMQECWRKEIAGVLHDLREKEKRFQTIEEELRNKE 438
            ||.||:|:..|||:  |..|..|.:  ||.:.:..||.||...|..|::.|:.....|:||:.:|
  Rat   250 RPSFKQIISILESM--SNDTNLPDQCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERE 312

  Fly   439 EQLLRVQNEQREKAN--LLK-----------------------------------IREQNLRERE 466
            .:|...:.:..|::|  ||.                                   .:|.|:..:.
  Rat   313 RRLKMWEQKLTEQSNTPLLPSFEIGAWTEEDVYFWVQQLVGKGESSVEMSGYASLFKENNITGKR 377

  Fly   467 RVLIERELVMLQPVPSKRK--HKKGKKNKPLQISLPTGFRHTITAVRDKAEQP--GSPSFSGLRI 527
            .:|:|.|.:....:.||..  |.|....|.....|  ...|....::|..|:|  .......|.:
  Rat   378 LLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDYL--NLFHFPPLIKDSGEEPEENEEKIVNLEL 440

  Fly   528 VALTDGHKGKTWGPSTMHQRERSLLPSQLSGGQPEWPAQTSTHSSFSKSAPNLDKKQQQQNQQQV 592
            |.      |....|.|..|..:..:..::.|  .|.........:|:.|.|:          .::
  Rat   441 VF------GFHLKPGTGPQDCKWKMYMEMDG--DEVAIAYIKDVTFNTSLPD----------AEI 487

  Fly   593 ASLTPPPG------LGILGGSGGAGGTPATPLLYP-------------GIPIILTRPNNNNIGNC 638
            ..:|.||.      :||:...     |....:.|.             .|.....:|.:    ..
  Rat   488 LKMTKPPFVMEKWIVGIVKDQ-----TVECTVTYESDVRTPKFTKHVHSIQWDRAKPQD----EV 543

  Fly   639 KAITTTITTTTTTTTNNNNNNNNSISANNNNQLNNISTINSNNNNNQTNL-TSQPNTII------ 696
            ||:...|.|..:::..|..:.::| ||:    ...:.|:......:.::| .||.|.|:
  Rat   544 KAVQLAIQTLFSSSEGNPGSRSDS-SAD----CQWLDTLRMRQIASHSSLQRSQSNPILGSPFFQ 603

  Fly   697 VLQNGRNNSNSSTTSQSPAKIYHRARSQEYGLDHPLAYQPPPLYLVTDDSSETDTVASPTGCFHF 761
            ...|..:.:.:...:|:|.|......|     .:|.....|..|.:|.:.|.....:..:|   |
  Rat   604 YFVNQDSYAAAVRRTQTPVKYQQITPS-----INPSRSSSPTQYGLTKNFSSLHLNSRDSG---F 660

  Fly   762 LKSGNSSAASGAV------HLHRFGGSLGNSPA---VGRKKHSLDSSSHHP------PANGSNSF 811
            ....:||:..|..      ..:|...||.:||.   .|:.:||..|...:|      |.:..|:.
  Rat   661 SSLNDSSSERGRYSDRSRNKYYRGSVSLNSSPKGRYGGKSQHSTPSRERYPGKFYRLPQSALNTH 725

  Fly   812 ALPNQLTLPSEDNNTYDHAFYRDV-----IKKMSMASSERVNSKSSGDLTM--YNSST--PLTAR 867
            ..|:....|    |.:|....:.:     ..:.:..:.|..:..|.|..|.  |...|  .|:|:
  Rat   726 QSPDFKRSP----NDHDRRAPKTIPGMPLHPETAPKAGEEESRVSEGGWTKVEYRKKTHRQLSAK 786

  Fly   868 DCDDAEEAFEGGRFQRNF 885
            ...|.......||  |||
  Rat   787 TSKDRTRGNYRGR--RNF 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		STKc_MLK	134..389	CDD:270963	101/261 (39%)
Map3k20	NP_001385922.1	STKc_MLTK	22..263	CDD:270962	101/260 (39%)
		SAM_MLTK	338..408	CDD:188928	10/69 (14%)