Protein Alignment slpr and Abl2

DIOPT Version :9

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_038946666.1
• Gene: Abl2 / 304883
• RGDID: 1590898
• Length: 1188
• Species: Rattus norvegicus
• Alignment Length: 1029
• Identity: 228/1029 - (22%)
• Similarity: 372/1029 - (36%)
• Gaps: 332/1029 - (32%)

  Fly    44 DGSLWTALYDYDAQGEDELTLRRGEIVVVLSTDSEVSGDVGWWT---GKIGDKVGVFPKDFVT-- 103
            |.:|:.||||:.|.|::.|::.:||.:.||..:..     |.|:   .|.|.  |..|.:::|
  Rat   108 DPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQN-----GEWSEVRSKNGQ--GWVPSNYITPV 165

  Fly   104 -----------------------------------DEDPLQLNVS-------------------- 113
                                               :..|.||::|
  Rat   166 NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTTDSKV 230

  Fly   114 --------SAIGDIQPH----------------------------------EIEYNELDIKEVIG 136
                    |.:.::..|                                  |:|..::.:|..:|
  Rat   231 YVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLG 295

  Fly   137 SGGFCKVHRGYYDGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKHENIAALRGVC-LNTKL 200
            .|.:.:|:.|.:  ::.::.:|.:|.::|...: :..|:||.:...:||.|:..|.||| |....
  Rat   296 GGQYGEVYVGVW--KKYSLTVAVKTLKEDTMEV-EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPF 357

  Fly   201 CLVMEYARGGSLNRIL----AGKIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYE 261
            .:|.||...|:|...|    ..::...||:..|.||:..|.||..:   :.|||||.:.|.|:.|
  Rat   358 YIVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKK---NFIHRDLAARNCLVGE 419

  Fly   262 AIEGNHLQQKTLKITDFGLAREMYNTQRMSAAGT---YAWMPPEVISVSTYSKFSDVWSYGVLLW 323
                ||:    :|:.||||:|.|......:.||.   ..|..||.::.:|:|..||||::|||||
  Rat   420 ----NHV----VKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLW 476

  Fly   324 ELIT-GETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLE 387
            |:.| |.:||.|.| ||..|.:......:..|:.||.....||::||:..|..||.|.|..:..|
  Rat   477 EIATYGMSPYPGID-LSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE 540

  Fly   388 SIACSKFTLTPQESFHYMQECWRK--------EIAGVLHDLREKEKRFQTIEEELRNKE------ 438
            ::....   :..|.|.:..|...:        .:...|..|.....:.:|::::..|||
  Rat   541 TMFHDS---SISEDFVFFTEVAEELGRTASSSSVVPYLPRLPLLPSKTRTLKKQGENKENLDGGL 602

  Fly   439 --EQLL--------------------RVQNEQREK--ANLLKIREQNLRERER-------VLIER 472
              .::|                    .:..:||:|  ::||:..::....|:|       .:.:|
  Rat   603 DASEILASSSAPAGFIRSTQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR 667

  Fly   473 ELVMLQPVPSKRK----------HKK----GKKNKPLQISLPTGFRHT----------------- 506
            .    .|:|.||.          |||    |..:....:....||..|
  Rat   668 N----APMPPKRSSSFREMENQPHKKYELTGNFSPVASLQHADGFSFTPGQQESNLVPAKCYGGS 728

  Fly   507 -----ITAVRDKAEQPGSPS----FSGL------RIVALTDG-HKGK-TWGPSTMHQRERSLLPS 554
                 :....|.....||.:    :||:      |::..|.| ..|| |....|.....||...|
  Rat   729 FAQRNLCGDDDSGGGGGSGTAAGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPRSNSTS 793

  Fly   555 QLSGGQPEWP--AQT-------------STHSSFSKSAPNLD-------KKQQQ----QNQQQVA 593
            .:|.|.||..  |.|             .|.|:.|:...|:|       ||.::    ..::..|
  Rat   794 SMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEEGAAPARERPKA 858

  Fly   594 SLTPP-------------------PGLGILG------GSGGAGGTPATPLLYPGIPIILTRPNNN 633
            .|.|.                   ||:|:.|      |....||   |.|...|:|....:|..:
  Rat   859 KLLPRGATALALRAPDPAITESDCPGVGVAGVAAAPKGKERNGG---TRLGVAGVPEDAEQPGWS 920

  Fly   634 NIGNCKAITTTITTTTTTTTNNNNNNNNSISANNNNQLNNISTINSNNNNNQTNLTSQPNTIIVL 698
            :  ..||:....||       :|:.....||....:...::..|.:::..|:..|.|:
  Rat   921 S--PAKAVAVLPTT-------HNHKVPVLISPTLKHTAADVQLIGTDSQGNKFKLLSE------- 969

  Fly   699 QNGRNNSNSSTTSQSPAKIYHRARSQEYGLDHPLAYQPPPLYLV-----TDDSSETDTVASPTGC 758
                :...||.....|.::..:.           |..|||:..:     |....|.:..|.|.|
  Rat   970 ----HQVTSSGDKDRPRRVKPKC-----------APPPPPVMRLLQHPSTCSDPEEEPTAPPAG- 1018

  Fly   759 FHF--LKSGNSSAASGAVHLHRFGGSLGNSPAVGRKKHSLDSSSHHPP--ANGS 808
            .|.  .:.|...||.|.|   ...|..|. |.:...:..|.:||..|.  |||:
  Rat  1019 QHTPDTQDGGKKAAPGPV---PSSGKPGR-PVMPPPQVPLPTSSISPAKMANGT 1068

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	19/96 (20%)
		TyrKc	129..386	CDD:197581	88/265 (33%)
		STKc_MLK	134..389	CDD:270963	88/263 (33%)
Abl2	XP_038946666.1	SH3_Abl	111..164	CDD:212784	18/59 (31%)
		SH2_ABL	169..262	CDD:198189	6/92 (7%)
		PTKc_Abl	281..543	CDD:270645	91/276 (33%)
		FABD	1069..1188	CDD:197885	228/1029 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100013
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X88
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810