DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slpr and Dstyk

DIOPT Version :9

Sequence 1:	NP_001188558.1	Gene:	slpr / 44111	FlyBaseID:	FBgn0030018	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_955750.1	Gene:	Dstyk / 304791	RGDID:	735051	Length:	927	Species:	Rattus norvegicus

Alignment Length:	227	Identity:	60/227 - (26%)
Similarity:	100/227 - (44%)	Gaps:	37/227 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 KHENIAALRGVCL--------NTKLCLVMEYARGGSLNRILAGKIPPDVLVNWAIQIARGMNYLH 240
            |||.:..|.|..:        :..:.|:||.........:.|| :..:..:..|:.:..|:.:||
  Rat   704 KHERLVDLHGSVIDYNYGGGSSVAVLLIMERLHRDLYTGLKAG-LSLETRLQIALDVVEGIRFLH 767

  Fly   241 NEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRM---SAAGTYAWMPPE 302
            ::   .::|||:|..|||:.        :|...||||.|..:    .:.|   |..||...|.||
  Rat   768 SQ---GLVHRDIKLKNVLLD--------KQNRAKITDLGFCK----PEAMMSGSIVGTPIHMAPE 817

  Fly   303 VISVSTYSKFSDVWSYGVLLWELITGETPY-KGFDPLSVAYGVAVNTLTLPIPKTCP----ETWG 362
            :.: ..|....||:::|:|.|.:.:|.... :.|:..:....:..|......|:..|    |.|
  Rat   818 LFT-GKYDNSVDVYAFGILFWYICSGSIKLPEAFERCASKDHLWNNVRRGTRPERLPVFDEECW- 880

  Fly   363 ALMKSCWQTDPHKRP--GF-KEILKQLESIAC 391
            .||::||..||.|||  |. :.||:.:....|
  Rat   881 QLMEACWDGDPSKRPLLGIVQPILRSIMDRLC 912

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		TyrKc	129..386	CDD:197581	59/220 (27%)
		STKc_MLK	134..389	CDD:270963	59/223 (26%)
Dstyk	NP_955750.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		PKc_Dusty	649..910	CDD:270877	59/223 (26%)
		S_TKc	651..895	CDD:214567	54/208 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900