DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slpr and Mos

DIOPT Version :9

Sequence 1:	NP_001188558.1	Gene:	slpr / 44111	FlyBaseID:	FBgn0030018	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_064487.3	Gene:	Mos / 24559	RGDID:	3103	Length:	342	Species:	Rattus norvegicus

Alignment Length:	309	Identity:	81/309 - (26%)
Similarity:	146/309 - (47%)	Gaps:	73/309 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 IEYNELDIKEVIGSGGFCKVHRGYYDGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWA------ 182
            |::.::.:...:|||||..|::..|.|..||||        .:.:...|:....:.|||
  Rat    57 IDWGQVCLLHRLGSGGFGSVYKATYHGVPVAIK--------QVNKCTRNLRASQRSFWAELNIAR 113

  Fly   183 LKHENIAALRGVCLNTKL--------CLVMEYARGGSLNRILAGKI-PPDVL-----------VN 227
            |.|:||  :|.|..:|:.        .::||:....:|::::.|.. .|:.|           :.
  Rat   114 LHHDNI--VRVVAASTRTPEGSNSLGTIIMEFGGNVTLHQVIYGATRSPEPLSCREQLSLGKCLK 176

  Fly   228 WAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSA 292
            :::.|..|:.:||::   ||:|.|||.:|:||.|        :...||:|||.::::.:.:...|
  Rat   177 YSLDIVNGLLFLHSQ---SILHLDLKPANILISE--------KDVCKISDFGCSQKLQDLRCRQA 230

  Fly   293 A-----GTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLP 352
            :     |||....||::.....:..:|::|:|:.||::.|.|.||.| :|..|.|.|....|.
  Rat   231 SLHHIGGTYTHQAPELLKGEIATPKADIYSFGITLWQMTTREVPYSG-EPQYVQYAVVAYNLR-- 292

  Fly   353 IPKTCPETWGA-------------LMKSCWQTDPHKRPGFKEILKQLES 388
                 |...||             :::|||:....:|||.:.:.|.|::
  Rat   293 -----PSLAGAVFTASLTGKTLQNIVQSCWEARALQRPGAELLQKDLKA 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		TyrKc	129..386	CDD:197581	79/300 (26%)
		STKc_MLK	134..389	CDD:270963	80/299 (27%)
Mos	NP_064487.3	STKc_Mos	58..329	CDD:270881	78/299 (26%)
Mos	NP_064487.3	S_TKc	64..331	CDD:214567	78/295 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810