DRSC/TRiP Functional Genomics Resources

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Protein Alignment slpr and Ankk1

DIOPT Version :9

Sequence 1:NP_001188558.1 Gene:slpr / 44111 FlyBaseID:FBgn0030018 Length:1155 Species:Drosophila melanogaster
Sequence 2:NP_001363880.1 Gene:Ankk1 / 244859 MGIID:3045301 Length:746 Species:Mus musculus


Alignment Length:543 Identity:120/543 - (22%)
Similarity:210/543 - (38%) Gaps:123/543 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   130 DIKE---VIGSGGFCKVHRGYYD--GEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKHENIA 189
            |.:|   ::.||||.||.:..:.  ..:.|||.:....::........:.:||.....:|.::|.
Mouse    32 DFEEEWHLVASGGFSKVFQARHKRWRTQYAIKCSPCLQKETTSSEVTCLFEEAVKMEKIKFQHIV 96

  Fly   190 ALRGVCLNTKLCLVMEYARGGSLNRILAGKIPPDVLVNWAIQI------ARGMNYLHNEAPMSII 248
            ::.||| ...|.:|||:...|||.:.|     |...:.|.:::      :..||:||:..| .::
Mouse    97 SIYGVC-KQPLGIVMEFMASGSLEKTL-----PTHSLCWPLKLRIIHETSLAMNFLHSIKP-PLL 154

  Fly   249 HRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNT------QRMSAAGTYAWMPPEVISVS 307
            |.|||..|:|:     .|::.   :||:||||::.|..:      :|.:..||.:::|||:...:
Mouse   155 HLDLKPGNILL-----DNNMH---VKISDFGLSKWMEQSTQKQYIERSALRGTLSYIPPEMFLEN 211

  Fly   308 TYSKFS--DVWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGA------- 363
            ..:...  ||:|:.:::||::|.:.||.|.:.:::...||..  ..|..:...:.|..       
Mouse   212 NKAPGPEYDVYSFAIVIWEILTQKKPYAGLNMMTIIIRVAAG--MRPSLQDVSDEWPEEVHQMVN 274

  Fly   364 LMKSCWQTDPHKRPGFKEILKQ--------------------LESIACSKFTLTPQESFHYMQEC 408
            |||.||..||.|||.|..:..:                    .:.::|......|    |.:.:.
Mouse   275 LMKRCWDQDPKKRPCFLNVAVETDMLLSLFQSPMTDPGCEALTQKVSCKPSLSQP----HKVSKE 335

  Fly   409 WRKEIA--GVLHD-----LREKEKRFQTIEEELRNKEEQL-LRVQNEQREKANLLKIRE-----Q 460
            ..:|||  .|..|     |:..:.:.....:...|:...| ..|.....|:..||...:     |
Mouse   336 VNQEIADSAVSSDSLKWILQLSDSKSLVASDVYENRVTPLHFLVAGGSLEQVRLLLSHDVDVDCQ 400

  Fly   461 NLRERERVLIERE--------LVMLQPVPSKRKHKKGKKNKPLQISLPTGFRHTITAVRDKAEQP 517
            .......:||..:        |::.....:....:.|.  .||..:...|..||...:.|..   
Mouse   401 TASGYTPLLIATQDQQPDLCALLLAHGADTNLADEDGW--APLHFAAQNGDDHTARLLLDHG--- 460

  Fly   518 GSPSFSGLRIVALTDGHKGKTWGPSTMH---------------QRERSLLPSQLSGGQPEWPAQT 567
                       ||.:..:.:.|.|  :|               .|:..|.|.:..|..|...|..
Mouse   461 -----------ALVNAREHEGWTP--LHLAAQNNFENVARLLVSRQADLSPHEAEGKTPLHVAAY 512

  Fly   568 STHSSFSK--SAPNLDKKQQQQN 588
            ..|....|  |....:...||:|
Mouse   513 FGHIGLVKLLSGQGAELDAQQRN 535

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slprNP_001188558.1 SH3_MLK 47..104 CDD:212809
TyrKc 129..386 CDD:197581 77/301 (26%)
STKc_MLK 134..389 CDD:270963 75/297 (25%)
Ankk1NP_001363880.1 PKc_like 37..305 CDD:389743 75/284 (26%)
PHA02876 <364..>694 CDD:165207 34/190 (18%)
ANK 1 370..399 6/28 (21%)
ANK repeat 373..401 CDD:293786 5/27 (19%)
ANK repeat 403..434 CDD:293786 3/30 (10%)
ANK 2 403..432 3/28 (11%)
ANK repeat 436..467 CDD:293786 9/46 (20%)
ANK 3 436..465 9/44 (20%)
ANK 4 469..498 5/30 (17%)
ANK repeat 469..497 CDD:293786 4/29 (14%)
ANK repeat 502..532 CDD:293786 6/29 (21%)
ANK 5 502..531 6/28 (21%)
ANK 6 535..564 1/1 (100%)
ANK repeat 537..566 CDD:293786
ANK repeat 568..599 CDD:293786
ANK 7 568..597
ANK 8 601..630
ANK repeat 602..632 CDD:293786
ANK repeat 634..665 CDD:293786
ANK 9 634..663
ANK repeat 667..698 CDD:293786
ANK 10 667..696
Ank_2 672..>742 CDD:372319
ANK repeat 700..730 CDD:293786
ANK 11 700..729
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0192
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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