Protein Alignment slpr and Y105C5A.24

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_502888.2
• Gene: Y105C5A.24 / 190882
• WormBaseID: WBGene00013643
• Length: 478
• Species: Caenorhabditis elegans
• Alignment Length: 452
• Identity: 110/452 - (24%)
• Similarity: 181/452 - (40%)
• Gaps: 100/452 - (22%)

  Fly   104 DEDPLQLNVSSAIGDIQPHEIEYNELDIKEVIGSGGFCKVHRGYY------DGEEVAIKIAHQTG 162
            |.|   |.::|.|..|.|:.|:  ||: ...:|.|.|..|.:..|      .....|||.|..|.
 Worm    24 DSD---LCLTSDIPKIPPNCID--ELN-SHFLGKGTFGVVEKTKYRKTRDDTYRPAAIKYASATH 82

  Fly   163 EDDMQRMRDNVLQEAKLFWALK-HENIAALRGVCLNTK--LCLVMEYARGGSLNRILAGK----I 220
            ...::|       |||..|.|: |.||..:.|:..:.:  ..|||||...|.:..::..:    .
 Worm    83 LSILKR-------EAKHMWNLRNHVNIIKIYGMYESHRNGQGLVMEYMDCGCVADLIYDRKNIEY 140

  Fly   221 PPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMY 285
            ..|.:.:|..|::..:|:.|::   ..||||||..|:|:      :| ..:||||.|||....::
 Worm   141 KMDHVASWMYQLSSAVNFFHSK---DQIHRDLKLQNMLL------SH-HHRTLKICDFGTFTSIH 195

  Fly   286 NTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPYKGFDPLS-VAYGVAVNTL 349
            .:. .|..|:...|.||:.....|:..:|::|.|:::|::|..:.||....|:: ..|.||...|
 Worm   196 QSM-TSNRGSPITMAPEIFRCEPYNMKADIFSIGIIMWQMIARDHPYTMNMPITPFLYNVATRNL 259

  Fly   350 TLPIPKTCPETWGALMKSCWQTDPHKRP----------------------------GFKEILKQL 386
            . |....|........|.||..:|..||                            |....:|..
 Worm   260 R-PHEIECNPILSNFYKRCWSDNPASRPTSADCVEYFRCLRSEYPNGNVPLWDPASGASNTVKIP 323

  Fly   387 ES-------IACSKFTLTPQESFHYMQECWRKEIAGVLHDLREKEKRFQTIEEELRNKEEQ---- 440
            :|       :...|..:||......:.....:|...:|.|..:..|    :|.::.|:||:
 Worm   324 KSQPGGRSPLPLPKTEITPDVKPKEVAPAKVQETPALLPDTLKVPK----VERQISNEEEKQKIF 384

  Fly   441 LLRVQNEQRE-------KANLLKIREQ----NLRERERVLIERELVMLQPVPSKRKHKKGKK 491
            :..:.||...       ..:.|::..|    ||...|.:|.::|.:       ..|||..:|
 Worm   385 MTALSNEDTRPIDPNEGDESSLELYHQHCLVNLNYAEVLLAKKEAI-------NEKHKLVQK 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	110/452 (24%)
		STKc_MLK	134..389	CDD:270963	76/303 (25%)
Y105C5A.24	NP_502888.2	Protein Kinases, catalytic domain	49..287	CDD:473864	72/256 (28%)