Protein Alignment slpr and C18H7.4

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_499953.2
• Gene: C18H7.4 / 182803
• WormBaseID: WBGene00015994
• Length: 390
• Species: Caenorhabditis elegans
• Alignment Length: 392
• Identity: 98/392 - (25%)
• Similarity: 170/392 - (43%)
• Gaps: 90/392 - (22%)

  Fly    50 ALYDYDAQGEDELTLRRGEIVVVLSTDSEVSGDVGWWTGKIGD------------KVGVFPKDFV 102
            ||.:.||   |:|.:..|:.:|.              |..:.|            |.|:...:..
 Worm    22 ALMNIDA---DQLLVNDGDFMVT--------------TRIVADLNKLQFHLAVRLKKGIRRYEIK 69

  Fly   103 TDEDPLQL------NVSSAIGDIQPHEIE--------------------YNELDIKEVIGSGGFC 141
            .:::..:|      |:...|..::...||                    :.:::.|:.||||.:.
 Worm    70 RNQNSAKLGNRSASNIGKLIDSLKAETIEIKGEKVILKRAIAKGKFQLMHTDVNFKKQIGSGAYG 134

  Fly   142 KVHRG--YYDGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKHENIAALRGVCL-NTKLCLV 203
            .|:||  ......||:|.....|.|: :.:.| :::||::.....|.||....|..| :....||
 Worm   135 TVYRGRLVKTNAIVAVKKLDTEGTDE-EGLTD-MMKEARVMQLYDHPNIVKFYGYILDDVPYLLV 197

  Fly   204 MEYARGGSLNRILAGKIPPDVLVNWAIQ----IARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIE 264
            :|:..|||:..:|..|  |::.:|..:|    .|.||:|||.:   :.||||:.|.|.||:..:
 Worm   198 LEFCNGGSVEDLLRDK--PEIKINRRVQYTYMAACGMDYLHKK---NCIHRDIASRNCLIHNGV- 256

  Fly   265 GNHLQQKTLKITDFGLAR--EMYNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELIT 327
                    :|:.|||:.|  .:|... :|......|:.|||.:.......:||:::||::||...
 Worm   257 --------VKMADFGMCRATAVYKVD-LSKPLNVRWLAPEVWTNGETRYNTDVYAFGVMIWEFFI 312

  Fly   328 GETPYKGFDPLSVAYGVAVNT-----LTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLE 387
              |||:  .|.:...|..|..     ..:..|:..|:...:|:..||..||.|||..:::.::||
 Worm   313 --TPYQ--SPYTEWKGYTVKQKVRGGYRMQPPEGMPKDVASLLAECWNHDPEKRPNAEKLKEKLE 373

  Fly   388 SI 389
            .:
 Worm   374 DL 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	12/65 (18%)
		STKc_MLK	134..389	CDD:270963	80/268 (30%)
C18H7.4	NP_499953.2	SH2_Fps_family	11..99	CDD:198224	16/93 (17%)
		PK_Tyr_Ser-Thr	122..372	CDD:462242	79/270 (29%)