Protein Alignment slpr and kin-24

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_501761.2
• Gene: kin-24 / 177829
• WormBaseID: WBGene00002206
• Length: 516
• Species: Caenorhabditis elegans
• Alignment Length: 486
• Identity: 114/486 - (23%)
• Similarity: 201/486 - (41%)
• Gaps: 108/486 - (22%)

  Fly    89 KIGDKVGVF--------PKDFVTDEDPLQLNVSSAIGDIQPH-----------------EIEYNE 128
            ::.|:.|.:        .::.||.|......:...||..|.|                 ::.:|.
 Worm    85 QVEDRAGEYYLMQELMEKEELVTRESKAFPTLEELIGHFQHHRLACKIRLGRPLKRPSWQLRHNS 149

  Fly   129 L--DIKEVIGSGGFCKVHRGYYDGE----EVAIKIAHQTGEDD--MQRMRDNVLQEAKLFWALKH 185
            :  |....:|||.||.|:||....:    .||||::..:.::.  :...|:.:|.||::.....:
 Worm   150 VVYDDTGKLGSGNFCIVYRGMLRKQGKIIPVAIKVSKNSDKESAALMETRNLLLAEARIMMNYNN 214

  Fly   186 ENIAALRGVCLNTKLCLV-MEYARGGSLNRILA--GK----IPPDVLVNWAIQIARGMNYLHNEA 243
            .|:..:.||..:....:| ||:..||||...|.  ||    ....:|:   |..||||.|||::
 Worm   215 INVIRIYGVACDVPPFMVCMEFCSGGSLEDALKKYGKDMEEFERQILL---IDAARGMRYLHDK- 275

  Fly   244 PMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQR----MSAAGTYAWMPPEVI 304
              ..:||||.|.|.||  :.:|      .:||.||||::.:...|:    .......||:.||.|
 Worm   276 --KCVHRDLASRNCLI--SFDG------IVKIADFGLSKTLEKDQKAFKEALKEAPLAWLAPECI 330

  Fly   305 S-VSTYSKFSDVWSYGVLLWELI-TGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKS 367
            . .|.:|..:|||::||:::|:. ..|..:.|.:.:::...:....:.....:|......|::.|
 Worm   331 QRESEFSTKTDVWAFGVVIFEVYNNAEKLFAGEEDIAILRKIKKANMPTIENRTKVPAMQAVLSS 395

  Fly   368 CWQTDPHKRPGFKEILKQLESIACSKFTLTPQESFHYMQECWRKEIAGVLH------DLREKEKR 426
            .|...|..||   |:.|.||.:..:...:.|.:    ::......:.||..      ||   |..
 Worm   396 IWTRKPDDRP---EMQKVLEKLVAALVPIQPDD----LKRLQINSLKGVSRTQMPNTDL---EMD 450

  Fly   427 FQTIEEEL-RNKEEQLLRVQNEQREKANLLKIREQNLRERERVLIERELVMLQPVPSKRKHKKGK 490
            ...:.||: ::..|:..:|:...::|..     .::.|..:|            .|.:.:..|.|
 Worm   451 VSVVNEEVDQDGSEKNRKVKGGSKKKTG-----NRHNRSGKR------------TPKQEESPKSK 498

  Fly   491 KNKPLQISLPTGFRHTITAVRDKAEQPGSPS 521
            |..||:.::..|              ||:.|
 Worm   499 KPVPLRNTVRKG--------------PGATS 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	3/22 (14%)
		STKc_MLK	134..389	CDD:270963	80/273 (29%)
kin-24	NP_501761.2	SH2	29..128	CDD:214585	9/42 (21%)
		STYKc	157..414	CDD:214568	80/273 (29%)