Protein Alignment slpr and R05H5.4

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_496201.1
• Gene: R05H5.4 / 174581
• WormBaseID: WBGene00011039
• Length: 414
• Species: Caenorhabditis elegans
• Alignment Length: 380
• Identity: 99/380 - (26%)
• Similarity: 164/380 - (43%)
• Gaps: 69/380 - (18%)

  Fly    50 ALYDYDAQGEDELTLRRGEIVVVLSTDSEVS------------GDVGW------WTGKIGDKV-- 94
            ||.:.||   |:|.:..|:.:|.:....:::            |...:      .|.|||.|.
 Worm    20 ALMNIDA---DQLLVNEGDFMVTMKKQLDINKLQLFLAVRLKKGIRRYEIKRTSKTAKIGGKTSQ 81

  Fly    95 GVFPKDFVTDEDPLQLNVSSAI-------GDIQPHEIEYNELDIKEVIGSGGFCKVHRG--YYDG 150
            .:.....:...||:::.....:       |..|   :.:.::..::.||:|.:..|:||  ....
 Worm    82 NIVKLINMLKADPIEIRGEKVVLKRAIPKGKFQ---LMHKDVIFQKKIGAGAYGTVYRGKLVKTD 143

  Fly   151 EEVAIKIAHQTG--EDDMQRMRDNVLQEAKLFWALKHENIAALRGVCL-NTKLCLVMEYARGGSL 212
            |.:|:|.....|  ||.:..|    ::||::.....|.||....|..| :....||:||..||::
 Worm   144 EVIAVKKLDPEGADEDGLAEM----MKEARVMQLYDHPNIVKFHGFILDDLPYLLVLEYCNGGAV 204

  Fly   213 N---RILAGKIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLK 274
            .   |....||.....|.:....|.||:|||.:   :.||||:.|.|.||::.:         :|
 Worm   205 EDRLRDKGEKIKVPTRVKYTYMAACGMDYLHKK---NCIHRDIASRNCLIHKGV---------VK 257

  Fly   275 ITDFGL--AREMYNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPYKGFDP 337
            :.|||:  |:.:|... :.......|:.|||.........:||:::|:::||..  |||:|  .|
 Worm   258 MADFGMCRAQSVYKVD-LKKPCNIRWLAPEVWDNGETRFNTDVYAFGIMMWEFF--ETPFK--SP 317

  Fly   338 LSVAYGVAVNTLT-----LPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLE 387
            ........|...|     ||.|.:.|.....:|..|||.|..|||..:|:.::||
 Worm   318 YVEMKAAQVKRKTRAGYRLPPPPSMPSRMVEIMSECWQVDAEKRPTAEELKEKLE 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	14/73 (19%)
		STKc_MLK	134..389	CDD:270963	81/269 (30%)
R05H5.4	NP_496201.1	SH2_Fps_family	9..97	CDD:198224	16/79 (20%)
		TyrKc	120..363	CDD:197581	77/263 (29%)