Protein Alignment slpr and kin-14

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_492004.1
• Gene: kin-14 / 172440
• WormBaseID: WBGene00002198
• Length: 418
• Species: Caenorhabditis elegans
• Alignment Length: 384
• Identity: 96/384 - (25%)
• Similarity: 158/384 - (41%)
• Gaps: 67/384 - (17%)

  Fly    57 QGEDELTLR-----------RGEIVVVLSTDSE-------VSGDVG---WWTGKIGDKVGVFPKD 100
            |..|||.::           .|::.::||...:       |:.|.|   |:.|.....:....:.
 Worm    38 QDADELLVKPGSFLLRASEVHGKMSMILSVRHDGKLHNIAVNSDTGENFWFEGHREKSIDQLVQW 102

  Fly   101 FVTDEDPLQ----LNVSSAIGD---IQPHEIEYNELDIKEVIGSGGFCKVHRGYYDGEEVAIKIA 158
            .:|...|:.    :.:...||.   |..||   |.:.||: :|.|.|.:|.....:.....::.|
 Worm   103 HMTTSTPITKTSGVKLKYPIGKADWIISHE---NVIFIKK-LGEGAFGEVSLAECEIGGRKVETA 163

  Fly   159 HQTGEDDMQR-MRDNVLQEAKLFWALKHENIAALRGVCL------------NTKLCLVMEYARGG 210
            .:|....|.| .|...::||:|.....|.:|..:.|..:            ...|.:|||....|
 Worm   164 VKTMRCQMTRDTRAAFMKEARLMRKYSHPHIVRIIGKIIVKHLPKVGLAVDAHPLMIVMEMCPHG 228

  Fly   211 SLNRIL---AGKIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKT 272
            ||...|   .||......:.:.|:.|.|:.||..:   ..:|||:.:.|.|:....:
 Worm   229 SLLSFLRKNKGKTTLSERLRFCIESADGLAYLEKK---QCLHRDIAARNCLLSITDQ-------- 282

  Fly   273 LKITDFGLA----REMYNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELIT-GETPY 332
            :||:||||:    .||::......  ...|:.|||:....||..||||::|||:||:.. |..||
 Worm   283 IKISDFGLSDDKRTEMHDDTLDKV--PVKWLAPEVMQDKLYSLKSDVWAFGVLMWEIYADGADPY 345

  Fly   333 KGFDPLSVAYGVAVNTLTLPIPKTCPETWGAL-MKSCWQTDPHKRPGFKEILKQLESIA 390
            .|...|.....:..:...:..|:|.|.|...: :|.||...|..|...|.:..:|:.::
 Worm   346 PGMTNLVTRAKIFCDDYRMTFPETTPPTISEIALKQCWAKLPSDRATMKTVHHKLKDLS 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	12/67 (18%)
		STKc_MLK	134..389	CDD:270963	74/276 (27%)
kin-14	NP_492004.1	SH2_Fps_family	26..110	CDD:198224	13/71 (18%)
		PTKc	138..401	CDD:270623	74/276 (27%)