Protein Alignment slpr and Matk

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_006513357.1
• Gene: Matk / 17179
• MGIID: 99259
• Length: 506
• Species: Mus musculus
• Alignment Length: 451
• Identity: 111/451 - (24%)
• Similarity: 177/451 - (39%)
• Gaps: 147/451 - (32%)

  Fly    61 ELTLRRGEIVVV---------------------------------LSTDSEVSGDVGWWTGKIGD 92
            ||..|:|::|.:                                 ||||.::| .:.|:.|||..
Mouse    65 ELAFRKGDMVTILEACEDKSWYRAKHHGSGQEGLLAAAALRQREALSTDPKLS-LMPWFHGKISG 128

  Fly    93 KV----------GVF--------PKDFV----------------------TDEDPLQLNVSSAIG 117
            :.          |:|        |.|:|                      .||.....|:...:.
Mouse   129 QEAIQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTIDEAVCFCNLMDMVE 193

  Fly   118 D------------IQPHE-----------------IEYNELDIKEVIGSGGFCKVHRGYYDGEEV 153
            .            ::|..                 ::...|.:...||.|.|..|.:|.|.|::|
Mouse   194 HYTKDKGAICTKLVKPRRKQGAKSAEEELAKAGWLLDLQHLTLGAQIGEGEFGAVLQGEYLGQKV 258

  Fly   154 AIK-----IAHQTGEDDMQRMRDNVLQEAKLFWALKHENIAALRGVCLNTKLCLVMEYARGGSLN 213
            |:|     :..|.           .|.|..:...|:|.|:..|.||.|:..|.:|||:...|:|.
Mouse   259 AVKNIKCDVTAQA-----------FLDETAVMTKLQHRNLVRLLGVILHHGLYIVMEHVSKGNLV 312

  Fly   214 RILAGK----IPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLK 274
            ..|..:    :....|:.:|:.:|.||.||.::   .::||||.:.|:|:.|.:        ..|
Mouse   313 NFLRTRGRALVSTSQLLQFALHVAEGMEYLESK---KLVHRDLAARNILVSEDL--------VAK 366

  Fly   275 ITDFGLA---REMYNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELIT-GETPYKGF 335
            ::|||||   |:..::.|:..    .|..||.:....:|..|||||:||||||:.: |..||...
Mouse   367 VSDFGLAKAERKGLDSSRLPV----KWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKM 427

  Fly   336 DPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEIL----KQLESIACS 392
            ....|:..|.......| |..||.:...||.|||:.:|.:||.|::|:    ::|.|:..|
Mouse   428 SLKEVSEAVEKGYRMEP-PDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKLGRELRSVGVS 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	19/115 (17%)
		STKc_MLK	134..389	CDD:270963	85/271 (31%)
Matk	XP_006513357.1	SH3	49..107	CDD:473055	5/41 (12%)
		SH2_csk_like	117..214	CDD:198190	14/97 (14%)
		Protein Kinases, catalytic domain	227..480	CDD:473864	85/279 (30%)