Protein Alignment slpr and Frk

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_034367.2
• Gene: Frk / 14302
• MGIID: 103265
• Length: 512
• Species: Mus musculus
• Alignment Length: 485
• Identity: 123/485 - (25%)
• Similarity: 192/485 - (39%)
• Gaps: 152/485 - (31%)

  Fly    28 PEIPIPDLEQVETQVGDGSLWTALYDYDAQGEDELTLRRGEIVVVLSTDSEVSGDVGWWTGK--- 89
            ||.|    ...|.:...|..:.||:||.|:..::|:.|.|:.:.||.|..|     |||..:
Mouse    38 PEAP----RSQEPERSHGQYFVALFDYQARTAEDLSFRAGDKLQVLDTSHE-----GWWLARHLE 93

  Fly    90 -----IGDKV-GVFPKDFVTDEDPLQL---------------------NVSSAI---------GD 118
                 :|.:: |..|.::|.::..||.                     |.:.|.         ||
Mouse    94 KKGTGLGQQLQGYIPSNYVAEDRSLQAEPWFFGAIKRADAEKQLLYSENQTGAFLIRESESQKGD 158

  Fly   119 ---------IQPH---------------------------------------------------- 122
                     :..|
Mouse   159 FSLSVLDEGVVKHYRIRRLDEGGFFLTRRKVFSTLNEFVNYYTTTSDGLCVKLEKPCLKIQVPTP 223

  Fly   123 -----------EIEYNELDIKEVIGSGGFCKVHRGYYDG-EEVAIKIAHQTGEDDMQRMRDNVLQ 175
                       ||:.|.:.:.:.:|||.|.:|..|.::. ..||:|.......|.     ::.|:
Mouse   224 FDLSYKTADQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDP-----NDFLR 283

  Fly   176 EAKLFWALKHENIAALRGVC-LNTKLCLVMEYARGGSLNRIL----AGKIPPDVLVNWAIQIARG 235
            ||::..:|:|..:..|..|| |...:.::.|..|.|||...|    ..||.....|:.|.|:|.|
Mouse   284 EAQIMKSLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDGGSKIHLIQQVDMAAQVASG 348

  Fly   236 MNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAR-------EMYNTQRMSAA 293
            |.||.::   :.|||||.:.|||:     |.|   ...|:.||||||       ::|.::. ...
Mouse   349 MAYLESQ---NYIHRDLAARNVLV-----GEH---NIYKVADFGLARVFKVDNEDIYESKH-EIK 401

  Fly   294 GTYAWMPPEVISVSTYSKFSDVWSYGVLLWELIT-GETPYKGFDPLSVAYGVAVNTLTLPIPKTC 357
            ....|..||.|..:.:|..|||||:|:||:|:|| |:.||.|.....|...::.| ..||.|..|
Mouse   402 LPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLSQN-YRLPQPSNC 465

  Fly   358 PETWGALMKSCWQTDPHKRPGFKEILKQLE 387
            |:.:.::|..||..:|.:||.|:.:..:||
Mouse   466 PQQFYSIMLECWNVEPKQRPTFETLHWKLE 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	19/65 (29%)
		STKc_MLK	134..389	CDD:270963	89/268 (33%)
Frk	NP_034367.2	SH3_Src_like	54..111	CDD:212779	18/61 (30%)
		SH2_Src_Frk	119..214	CDD:199831	6/94 (6%)
		PTKc_Frk_like	232..501	CDD:270653	92/282 (33%)