Protein Alignment slpr and Fgfr3

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_001156689.1
• Gene: Fgfr3 / 14184
• MGIID: 95524
• Length: 802
• Species: Mus musculus
• Alignment Length: 332
• Identity: 101/332 - (30%)
• Similarity: 152/332 - (45%)
• Gaps: 52/332 - (15%)

  Fly   105 EDPLQLNVSSAIGDIQPH-EIEYNELDIKEVIGSGGFCKVHRGYYDGEE---------VAIKIAH 159
            |.|:..|||.......|. |:....|.:.:.:|.|.|.:|......|.:         ||:|:..
Mouse   443 EGPVLANVSELELPADPKWELSRTRLTLGKPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLK 507

  Fly   160 QTGEDDMQRMRDNVLQEAKLFWALKHENIAALRGVCL-NTKLCLVMEYARGGSLNRILAGKIPPD 223
            ....|  :.:.|.|.:...:....||:||..|.|.|. ...|.:::|||..|:|...|..:.||.
Mouse   508 DDATD--KDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPG 570

  Fly   224 V------------------LVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQ 270
            :                  ||:.|.|:||||.||   |....|||||.:.|||:.|        .
Mouse   571 MDYSFDACRLPEEQLTCKDLVSCAYQVARGMEYL---ASQKCIHRDLAARNVLVTE--------D 624

  Fly   271 KTLKITDFGLAREMYNTQ--RMSAAG--TYAWMPPEVISVSTYSKFSDVWSYGVLLWELIT-GET 330
            ..:||.||||||:::|..  :.:..|  ...||.||.:....|:..|||||:||||||:.| |.:
Mouse   625 NVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGS 689

  Fly   331 PYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIACSKFT 395
            ||.|. |:...:.:......:..|.:|......:|:.||...|.:||.||::::.|:.|    .|
Mouse   690 PYPGI-PVEELFKLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRI----LT 749

  Fly   396 LTPQESF 402
            :|..:.:
Mouse   750 VTSTDEY 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		STKc_MLK	134..389	CDD:270963	90/287 (31%)
Fgfr3	NP_001156689.1	ig	46..110	CDD:395002
		Ig strand B	55..59	CDD:409353
		Ig strand C	69..73	CDD:409353
		Ig strand E	91..94	CDD:409353
		Ig strand F	104..108	CDD:409353
		IgI_2_FGFR	145..239	CDD:409443
		Ig strand A	145..148	CDD:409443
		Ig strand A'	156..161	CDD:409443
		Ig strand B	165..173	CDD:409443
		Ig strand C	179..184	CDD:409443
		Ig strand C'	187..189	CDD:409443
		Ig strand D	198..201	CDD:409443
		Ig strand E	205..210	CDD:409443
		Ig strand F	219..226	CDD:409443
		Ig strand G	229..239	CDD:409443
		IgI_3_FGFR	247..347	CDD:409363
		Ig strand A	247..250	CDD:409363
		Ig strand A'	254..258	CDD:409363
		Ig strand B	266..273	CDD:409363
		Ig strand C	277..284	CDD:409363
		Ig strand D	299..304	CDD:409363
		Ig strand E	315..320	CDD:409363
		Ig strand F	328..336	CDD:409363
		Ig strand G	339..347	CDD:409363
		PTKc_FGFR3	455..788	CDD:173652	96/320 (30%)