Protein Alignment slpr and Btk29A

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_061512228.1
• Gene: Btk29A / 1277670
• VectorBaseID: AGAMI1_007842
• Length: 810
• Species: Anopheles gambiae
• Alignment Length: 576
• Identity: 146/576 - (25%)
• Similarity: 214/576 - (37%)
• Gaps: 218/576 - (37%)

  Fly     3 PISEEQQ--LQQQQ-------QQQQ---LEQ------LHH------------------PQIPEI- 30
            |.:.:||  |||||       ||||   |:|      .||                  ||.|.:
Mosquito   260 PAASQQQVHLQQQQAALQAALQQQQPPLLQQQTSQQSSHHLNSSSSSLGNITPTFVAQPQSPTVN 324

  Fly    31 --PIPDLEQVETQVGDG---------------------------SLWTALYDYDAQGEDELTLRR 66
              ....|..|...|..|                           .:..|||.:.|....:|:|.:
Mosquito   325 SFKTASLNGVGLHVNGGGDLNMPGGPTVTPGTPNTKAKDVSPRVKIVVALYPFKAIESGDLSLEK 389

  Fly    67 GEIVVVLSTDSEVSGDVGWWTGKIGDK---VGVFPKDFVTDEDPLQL-NVSSAIGDI-------- 119
            .....|:....|     .||  |:.|:   :|..|.::|.:::.|.| .....:||:
Mosquito   390 NAEYEVIDDSQE-----HWW--KVKDQHGTIGYIPSNYVKEKELLGLQKYDWYVGDMSRQRAESL 447

  Fly   120 ------------------------------QPH-------------------------------- 122
                                          |.|
Mosquito   448 LKQNDKEGCFVVRKSSTKGLYTLSLHTKVPQSHVKHYHIKQNARSEFYLSEKHCCETIPDLINYH 512

  Fly   123 -------------------------------EIEYNELDIKEVIGSGGFCKVHRGYYDGE-EVAI 155
                                           ||..:||.|.|.:|||.|..|.|..:.|. :.|:
Mosquito   513 RHNSGGLACRLKTSPCDRPVPPTAGLSHDKWEIHPSELMILEELGSGQFGVVRRAKWRGSIDTAV 577

  Fly   156 KI--AHQTGEDDMQRMRDNVLQEAKLFWALKHENIAALRGVCLNTK-LCLVMEYARGGSL----- 212
            |:  .....|||.       ::|||:...|:|.|:..|.|||...: :.::.||.:.|||
Mosquito   578 KMMKVGTMSEDDF-------IEEAKVMTKLQHPNLVQLYGVCSKHRPIYIITEYMKHGSLLNYLR 635

  Fly   213 --NRILAGKIPPDVLVNWAIQIARGMNYL--HNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTL 273
              .:.|.|.:  .:|::..||:.:||:||  ||     .|||||.:.|.|:     |:   :.|:
Mosquito   636 RHEQSLIGNM--GLLLDMCIQVCKGMSYLERHN-----YIHRDLAARNCLV-----GS---ENTV 685

  Fly   274 KITDFGLAREMYNTQRMSAAGT---YAWMPPEVISVSTYSKFSDVWSYGVLLWELIT-GETPYKG 334
            |:.||||||.:.:.|..|:.||   ..|.||||::.:.:|..||||:||||:||:.| |:.||..
Mosquito   686 KVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEVFTCGKMPYGR 750

  Fly   335 FDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIA 390
            .....|...|. ..:.|..||.|.:....:||.||...|..||||:.:..||.::|
Mosquito   751 LKNTEVVERVQ-RGIILEKPKACAKEIYDVMKKCWSHSPEDRPGFRILKDQLAAVA 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	15/59 (25%)
		STKc_MLK	134..389	CDD:270963	95/271 (35%)
Btk29A	XP_061512228.1	None