Protein Alignment slpr and LOC1273258

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_061507028.1
• Gene: LOC1273258 / 1273258
• VectorBaseID: AGAMI1_012797
• Length: 1261
• Species: Anopheles gambiae
• Alignment Length: 1290
• Identity: 486/1290 - (37%)
• Similarity: 622/1290 - (48%)
• Gaps: 332/1290 - (25%)

  Fly     6 EEQQLQQQQQQQQLEQLHHPQIPEIPIPDLEQVETQVGDGSLWTALYDYDAQGEDELTLRRGEIV 70
            |....::|:.|||...:..|                     ||||.|||:|||:|||:||.|:||
Mosquito     8 ERSGSREQRDQQQDWVMMSP---------------------LWTARYDYEAQGDDELSLRVGQIV 51

  Fly    71 VVLSTDSEVSGDVGWWTGKIGDKVGVFPKDFVTDEDPLQLNVSSAIGDIQPHEIEYNELDIKEVI 135
            .||||||.:|||.|||||||||:||:||.:|||:|||       |:..:||.||:|:|||:||||
Mosquito    52 YVLSTDSSISGDEGWWTGKIGDRVGIFPSNFVTNEDP-------AVLKVQPVEIQYHELDLKEVI 109

  Fly   136 GSGGFCKVHRGYYDGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKHENIAALRGVCLNTK- 199
            |.|||.||||.:.:|||||:|.:.|  :|:.:..|.||||||||||:|||.||.:|:||||:.|
Mosquito   110 GVGGFSKVHRAFLNGEEVAVKASRQ--DDEFEVARQNVLQEAKLFWSLKHPNIVSLKGVCLDPKT 172

  Fly   200 LCLVMEYARGGSLNRILAG-KIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAI 263
            ||||||||||||||:|||| ||||:|||:|||||||||.|||.|||:|:||||||||||||.|:|
Mosquito   173 LCLVMEYARGGSLNKILAGRKIPPNVLVDWAIQIARGMKYLHCEAPISVIHRDLKSSNVLISESI 237

  Fly   264 EGNHLQQKTLKITDFGLAREMYNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITG 328
            :..||..|||||||||||||.|.|.|||||||:||||||||...||||.|||||||||||||:||
Mosquito   238 QHGHLLNKTLKITDFGLAREAYRTTRMSAAGTFAWMPPEVIKSGTYSKASDVWSYGVLLWELLTG 302

  Fly   329 ETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIACSK 393
            ||||||||.||||||||||||.|||||||||:||.||||||:.|||:||.||:|.|.|:.||.|.
Mosquito   303 ETPYKGFDSLSVAYGVAVNTLALPIPKTCPESWGKLMKSCWEIDPHRRPSFKDIEKDLDIIARSG 367

  Fly   394 FTLTPQESFHYMQECWRKEIAGVLHDLREKEKRFQTIEEELRNKEEQLLRVQNEQREKANLLKIR 458
            |..||.||||.||:.|:||||.||.:||:|||.|::.|||||:|||:|.|||.|||.|...|..|
Mosquito   368 FAQTPHESFHTMQDGWKKEIAEVLQELRKKEKAFKSFEEELRSKEEELTRVQQEQRYKEENLAKR 432

  Fly   459 EQNLRERERVLIERELVML----QPVPSKRKHKKGK------KNKPLQISLPTGFRHTI----TA 509
            ||.|..||..|:.|||.:|    .|.|.|||.|..|      |..|.|||||:.|||||    ||
Mosquito   433 EQELHAREIELLGRELKILINQNTPTPKKRKGKFSKSRIKLIKKAPGQISLPSDFRHTITIQHTA 497

  Fly   510 VRDKAEQ----PGSPSFSGLRIVALTDGHKGKTWGPSTMHQRERSLLPSQLSGGQPEWPAQTSTH 570
            :||:.::    ||||:.....||...|..|||||||||:||||||.||:.....:|:
Mosquito   498 IRDERQRIDTPPGSPATRLRTIVFPGDVIKGKTWGPSTLHQRERSHLPTMRPSARPQ-------- 554

  Fly   571 SSFSKSAPNLDKKQ-----QQQNQQQV-----------ASLTPPPGLGILGGSGGAGGTPATPLL 619
             .||||||||||.:     ...::.::           |||             |||  |.|
Mosquito   555 -QFSKSAPNLDKSRATALSASSSRHEILDYDTDEAWYAASL-------------GAG--PCT--- 600

  Fly   620 YPGIPIILTRPNNNNIGNCKAITTTITTTTTTTTNNNNNNNNS-ISANNNNQLNNISTINSNNNN 683
              .:..:...|..:::.....:.:|:...|...:........| |.....|..:.:::|.|..:.
Mosquito   601 --DVSTLSVAPLCSSLNRYGTLPSTVPMPTLYASEGQRKPKLSIIELVLYNMASMLASIASGYDV 663

  Fly   684 NQTNLTS-QPNTIIVLQNGRNNSNSSTTSQSPAKIYHRARSQEYGLDHPLAYQ----------PP 737
            ..:|:|. .|.    |..|......|.:  .|...||..|.|...:..|.|.|          ||
Mosquito   664 RVSNVTPLHPR----LHPGPLQPYESYS--QPVSPYHHHRHQLPPMVDPHALQLEGMVRLDGMPP 722

  Fly   738 PL------------------------------------YLVTDDSSETDTV----ASPTGCFHFL 762
            .|                                    |..|.:......|    .||......|
Mosquito   723 SLPPAPHTVDNALSQEAYEEELAQQAQDDRLYAQHSTPYQETPERQRPRKVHTQSTSPRQDERAL 787

  Fly   763 KSGNSSAASGAVHLHRFGGSLGNSPAVGRKKHSLDSSSHHPPANGSNSFAL--PNQLTLPSEDNN 825
            |..:|..       |....::..:..:|         |::.|:..|:||::  ..|...||..
Mosquito   788 KYTDSPQ-------HYLPSTMSTTSGLG---------SNYTPSGPSSSFSVGAGTQPPTPSPR-- 834

  Fly   826 TYDHAFYRDVIKKMSMAS-------SERVNSKSS----GDLTMYNSSTPLTARDCDDAEEAFEGG 879
                       :|.|.||       .|...|::.    |:...|....|:.......|..::.|.
Mosquito   835 -----------RKSSAASFMDFGDLPEERESRAGLYIPGEYDGYTQHNPIFTAGTRGATSSYIGS 888

  Fly   880 RFQRNFSGSQFPR----HCFFTRQEEE--GEAEDEDAVAAEVDTADADADDECQVPASQMRQNST 938
            .:        ||.    :..|.|:.:.  ||...||
Mosquito   889 HY--------FPYRPAINFAFERETKSYGGEPVYED----------------------------- 916

  Fly   939 TSRKSSVTFQSVSFE----EPDFVATPRTTARSDLYTSSASISFATYRSASPSLSSSSTTASASP 999
             ....|.::...::|    .|...|:.|.|...   ..:..||.|.:|....|:||
Mosquito   917 -HHYDSASYHDYAYEGPAGGPSGTASARATGTR---VPTMGISAAGHRRTHSSISS--------- 968

  Fly  1000 SIASTEAVNGYHMQENSI--LNTRRMQDVQ-------------------PHPDVIKLRAQEQRQQ 1043
            ::.|:....|:||:.:.:  ..||.:.||.                   |.|...||.
Mosquito   969 TLHSSNVNQGFHMEGDEMDGAGTRLIDDVTYKLGDLYLPGGGTDAASRLPAPSTAKLH------- 1026

  Fly  1044 TKNQKKQRPKHITKSKSVEAPVEGQHHEHDDHNDPQHQHHSAGSSKIRALFNLFTR----SRKKY 1104
                              |:|:....|.    :...||:.:..        |.|.|    .:..|
Mosquito  1027 ------------------ESPLPAAFHA----SSRMHQYENVP--------NFFRRQSSLQQAHY 1061

  Fly  1105 SKLAEHN-------MVGG----PEFCAIDPYQT-DLAMGGSSRSLKRKGKKPQTQ 1147
            |..:.|:       |.||    ||   ..||.. .|...|:...|.....:|||:
Mosquito  1062 SPSSAHSGHLSGDFMSGGAIPEPE---ERPYTVLGLTEHGADGGLLSSSLRPQTK 1113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	42/56 (75%)
		STKc_MLK	134..389	CDD:270963	193/256 (75%)
LOC1273258	XP_061507028.1	None