Protein Alignment slpr and Bmx

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_033889.2
• Gene: Bmx / 12169
• MGIID: 1101778
• Length: 655
• Species: Mus musculus
• Alignment Length: 292
• Identity: 87/292 - (29%)
• Similarity: 141/292 - (48%)
• Gaps: 31/292 - (10%)

  Fly   107 PLQLNVSSAIGDIQPHEIEYNELDIKEVIGSGGFCKVHRGYYDGE-EVAIKIAHQTGEDDMQRMR 170
            |:.:.:.|.|.:::..||..    :|| :|:|.|..|..|.:.|: :||:|:..:....:
Mouse   380 PVSVALGSGIWELKREEITL----LKE-LGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSE----- 434

  Fly   171 DNVLQEAKLFWALKHENIAALRGVCLNT-KLCLVMEYARGGSLNRILA--GK-IPPDVLVNWAIQ 231
            |...|||:....|.|..:....|||... .:.:|.||...|.|...|.  || :....|:.....
Mouse   435 DEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHGKGLESCQLLEMCYD 499

  Fly   232 IARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSAAGT- 295
            :..||.:|.:.   ..|||||.:.|.|:...:        ::|::|||:.|.:.:.|.:|:.||
Mouse   500 VCEGMAFLESH---QFIHRDLAARNCLVDSDL--------SVKVSDFGMTRYVLDDQYVSSVGTK 553

  Fly   296 --YAWMPPEVISVSTYSKFSDVWSYGVLLWELIT-GETPYKGFDPLSVAYGVAVNTLTLPIPKTC 357
              ..|..|||.....||..||||::|:|:||:.: |:.||..:|...|...|:... .|..|:..
Mouse   554 FPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGH-RLYRPQLA 617

  Fly   358 PETWGALMKSCWQTDPHKRPGFKEILKQLESI 389
            .:|...:|.|||...|.|||.|:::|..:|.:
Mouse   618 SDTIYQIMYSCWHELPEKRPTFQQLLSAIEPL 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		STKc_MLK	134..389	CDD:270963	80/263 (30%)
Bmx	NP_033889.2	PH_Btk	25..151	CDD:269944
		SH2_Tec_Bmx	269..374	CDD:198262
		Protein Kinases, catalytic domain	392..647	CDD:473864	83/276 (30%)