Protein Alignment slpr and map3k13

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_002936577.1
• Gene: map3k13 / 100493878
• XenbaseID: XB-GENE-5753317
• Length: 963
• Species: Xenopus tropicalis
• Alignment Length: 1078
• Identity: 292/1078 - (27%)
• Similarity: 435/1078 - (40%)
• Gaps: 278/1078 - (25%)

  Fly     4 ISEEQQLQQQQQQQQLEQLHHPQIPEIPIPDLEQVETQVGDGSLWTALYDYDAQGEDELTL---R 65
            :||:   .:.|.:..:.||.....||...|   |..:..|||.        ...|.:::.:   |
 Frog    73 VSED---SRDQFENSVLQLRDQDEPENTAP---QGSSPSGDGG--------SNSGNEDIRIHFSR 123

  Fly    66 RGEIVVVLSTDSEVSGDVGWWTGKIG---DKVGVFPKDFVTDEDPLQLNVSSAIGDIQPHEIEYN 127
            .|            ||:.|:..|..|   ....:..|.:.||....|.:.         .|:.:.
 Frog   124 SG------------SGNGGFLEGLFGCLRPVWNIIGKAYSTDYKLQQQDT---------WEVPFE 167

  Fly   128 ELDIKEVIGSGGFCKVHRGYYDGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKHENIAALR 192
            |:...:.:|||....|..|.:.|||||||...:..|.|::.:|           .|||.||.|.:
 Frog   168 EISELQWLGSGAQGAVFLGKFRGEEVAIKKVREQKETDIKHLR-----------KLKHPNIIAFK 221

  Fly   193 GVCLNTK-LCLVMEYARGGSLNRIL-AG-KIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKS 254
            |||.... .||:|||...|.|..:| || |:.|.:||:|:..||.||||||..   .||||||||
 Frog   222 GVCTQAPCYCLIMEYCAHGQLYEVLRAGRKVTPRLLVDWSTGIASGMNYLHLH---KIIHRDLKS 283

  Fly   255 SNVLIYEAIEGNHLQQKTLKITDFGLAREMYN-TQRMSAAGTYAWMPPEVISVSTYSKFSDVWSY 318
            .|||:..|        .|:||:|||.::|:.: :.:||.|||.|||.||||.....|:..|:||:
 Frog   284 PNVLVTHA--------DTVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSF 340

  Fly   319 GVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEIL 383
            |||||||:|||.|||..|..::.:||..|:|.||:|.|||:.:..|||..||:.|..||.|::||
 Frog   341 GVLLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQIL 405

  Fly   384 KQLESIACSKFTLTPQESFHYMQECWRKEIAGVLHDLREKEKRFQTIEEE---LRNKEEQLLRVQ 445
            ..|: ||.:....||||::...|..||:|:          :|.|:.|:.|   :...:|:|:|.:
 Frog   406 MHLD-IASADVLGTPQETYFKSQAEWREEV----------KKHFEKIKSEGTCIHRLDEELIRRR 459

  Fly   446 NEQREKANLLKIREQNLRERER---VLIERELVMLQ-PVPSK---RKHKKGKKNKPLQISLPTGF 503
            .|:...|  |.|||...|:.||   :.:|...:||| .|..|   |:.:..:|..|     .|..
 Frog   460 REELRHA--LDIREHYERKLERANNLYMELSSIMLQLEVREKELIRREQAVEKKYP-----GTYK 517

  Fly   504 RHTI------TAVRDKAEQPGSPSFSGLRIVALT--------DGHKGKTWGPSTMHQRERSLLPS 554
            ||.:      .:|....::.|.||    |:.:.|        ||          :...|.|...:
 Frog   518 RHPVRPIVHPNSVEKLIKKKGPPS----RVPSQTKRPDLLKSDG----------IVSAEGSAASA 568

  Fly   555 QLSGGQPEWPAQTSTHSSFSKSAPNLDKKQQQQN-------------QQQVASLTPPPGLGILGG 606
            ....|.|:      |.|...||......:.::.|             ||:    :|.|     ..
 Frog   569 SPISGSPK------TSSGAGKSRYRSKPRHRRGNSKGSHADFVGVLKQQE----SPIP-----SQ 618

  Fly   607 SGGAGGTPATPLLYPGIPIILTRPNNNNIGNCKAITTTITTTTTTTTNNNNNNNNSISANNNNQL 671
            ......|||:|      |:....|.:.         |:...||...|.|.:..|.:..|||....
 Frog   619 QSSQHHTPASP------PVTPCSPYHE---------TSQVMTTRHQTLNVHGQNIANCANNLRYF 668

  Fly   672 NNISTINSN-NNNNQTNLT-SQPNTIIVLQNGRNNSNSSTTSQSPAKIYHRARSQEYGLDHPLAY 734
            ...:.:.|. :::.|..|: |.|:.:            |:|.::.::| ...|..:|....|  |
 Frog   669 GPAAALRSPLSSHAQRRLSGSSPDLL------------SSTLEADSRI-QPEREYDYCQQDP--Y 718

  Fly   735 QPPPLYLVTDDSSETDTVASPTGCFHFLKSGNSSAASGAVHLHRFG-GSLGNSPAVGRKKHSLDS 798
            .|.|.........:|||             ||.:..:.....:|.. |....||     :|:|..
 Frog   719 NPCPGCTEASVQQDTDT-------------GNWNNTNMVTAEYRTSDGDPPESP-----RHNLVP 765

  Fly   799 SSHHPPANGSNSFAL------PNQLTLPSEDNNTYDHAFYRDV--IKKMSMASSERVNSKSSGDL 855
            .::..|.:|...|..      .:.||:|:..      |..|.:  ::|....|||    :..|::
 Frog   766 ENYEKPESGGEQFTSLKAAIGVSALTVPTPP------ALPRRIRTLRKNGDESSE----EEEGEV 820

  Fly   856 TMYNSSTPLTARDCDDAEEAF-EGGRFQRNFSGSQ----FPRHCFFTRQEEEGEAEDE----DAV 911
                           |:|..| ...|..|..|..|    |....|.....|||...|.    |.|
 Frog   821 ---------------DSEVEFPRRHRPPRGMSSCQSYSTFSSENFSVSDGEEGNTSDHSNSPDDV 870

  Fly   912 AA----------------------EVD-TADADADDECQVPASQMRQNSTTSRKSSVTFQSVSFE 953
            |.                      |:. .:|..:|.||.|          ...|:.::...:..|
 Frog   871 AGGDKIWHGDKLDDLLSQTPEIPIEISMQSDGLSDKECAV----------RRVKTQMSLGKLCTE 925

  Fly   954 EPDFVATPRTTARSDLYTSSASISFATYRSASPSLSSS 991
            |.:: ......|.||..:|....|.||.|:.:|..||:
 Frog   926 EHNY-ENAGNFAESDCDSSEGECSDATVRTNNPVNSST 962

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	9/62 (15%)
		STKc_MLK	134..389	CDD:270963	118/258 (46%)
map3k13	XP_002936577.1	STKc_MAP3K12_13	175..411	CDD:270961	118/258 (46%)