Protein Alignment slpr and map3k10

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_002938858.3
• Gene: map3k10 / 100488058
• XenbaseID: XB-GENE-920944
• Length: 990
• Species: Xenopus tropicalis
• Alignment Length: 1072
• Identity: 381/1072 - (35%)
• Similarity: 493/1072 - (45%)
• Gaps: 250/1072 - (23%)

  Fly    37 QVETQVGDGSLWTALYDYDAQGEDELTLRRGEIVVVLSTDSEVSGDVGWWTGKIGDKVGVFPKDF 101
            :|::......||.|::||:|..|:||||.||::|.:||.||.||||.|||||||.||||:||.::
 Frog    27 EVQSYGVSNPLWMAVFDYEATAEEELTLHRGDLVEILSKDSTVSGDEGWWTGKIKDKVGIFPSNY 91

  Fly   102 VTDED--------PLQLNVSSAIGDIQPHEIEYNELDIKEVIGSGGFCKVHRGYYDGEEVAIKIA 158
            |..::        |.|..:        |.|||:.||:::|:||.|||.||::|.:.|:|||:|..
 Frog    92 VVSDNKYTTLTGAPKQCPL--------PLEIEFEELNLEEIIGVGGFGKVYKGLWRGDEVAVKAV 148

  Fly   159 HQTGEDDMQRMRDNVLQEAKLFWALKHENIAALRGVCLN-TKLCLVMEYARGGSLNRILAG-KIP 221
            ....::|:....:||.||||||..|.|.||.||:||||. ..|||||||||||.|:|.||| |:|
 Frog   149 RHDPDEDINVTAENVRQEAKLFCMLCHPNIIALKGVCLKPPHLCLVMEYARGGPLHRALAGKKVP 213

  Fly   222 PDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYN 286
            ..||||||:|||||||||||||.:.||||||||||:||.|.:|.:.|..|||||||||||||...
 Frog   214 AHVLVNWAVQIARGMNYLHNEAIVPIIHRDLKSSNILILEKVEHDDLFNKTLKITDFGLAREWQK 278

  Fly   287 TQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTL 351
            |.:||||||||||.||||.:|.:||.|||||:|||||||:|||.||:..|.|:||||||:|.|||
 Frog   279 TTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTL 343

  Fly   352 PIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIACSKFTLTPQESFHYMQECWRKEIAGV 416
            |||.||||.:..::::||..|||.||.|..||:||.:|..|.....|.||||.:||.||.||..:
 Frog   344 PIPSTCPEPFVRILEACWDPDPHSRPSFSCILEQLTTIEQSAMFQMPLESFHSLQEDWRLEIQQM 408

  Fly   417 LHDLREKEKRFQTIEEELRNKEEQLLRVQNEQREKANLLKIREQNLRERERVLIEREL--VMLQP 479
            ..:||.|||       |||::||:|:|...|||....:||.|||.|.|||..::||||  :|.|.
 Frog   409 FDELRTKEK-------ELRSREEELVRAAEEQRILEEMLKRREQELAEREIDIVERELNIIMYQM 466

  Fly   480 VPSKRKHKKGKKN---------KPLQISLPTGFRHTITA----VRDKAEQPGSPSFS-------- 523
            ...|.|.||.|.|         ...:||||:||.|.||.    ..||.:..||.|:|
 Frog   467 YQEKPKVKKRKGNFKKSRLKLKDGNRISLPSGFEHKITVQASPTLDKCKGQGSSSYSPPGSPLII 531

  Fly   524 -GLRIVALT--DG--------------------HKGKTWGPSTMHQRERSLLPSQLSGGQPEWPA 565
             .||.:.||  ||                    .||:|||||:..|:||       :||:.....
 Frog   532 PRLRAIRLTPVDGSKTWGRSSVLKKDEVNTSNKKKGRTWGPSSTQQKER-------AGGEERLKT 589

  Fly   566 QTSTHSSFSKSAPNLDKKQQQQN-QQQVASLTPPPGLGILGGSGGAGGTPATPLLYPGIPIILTR 629
            .......:|.|||||.|..:... ....||||.........||     .|.:|.   .....||.
 Frog   590 LGEGSKQWSSSAPNLGKSPKHTPISVGFASLTEMEEYADADGS-----VPQSPY---SAQSYLTL 646

  Fly   630 PNNNNIGNCKAITTTITTTTTTTTNNNNNNNNSISANNNNQLNNISTINSNNNNNQTNLTSQPNT 694
            |..:::                                            .|:...|:..:.|
 Frog   647 PAQSDL--------------------------------------------RNHPEDTSQAAAP-- 665

  Fly   695 IIVLQNGRNNSNSSTTSQSPAKIYHRARSQEYGLDHPLAYQPPPLYLVTDDSSETDTVASPTGCF 759
                           :|.||.:.....|..|..|                           .||.
 Frog   666 ---------------SSDSPKRGSQSRRKSELVL---------------------------LGCA 688

  Fly   760 HFLKSGNSSAASGAVHLHRFGGSL-----------GNSPAVGRKKHSLDSSSHHPPANGSNSFAL 813
            ..|         .||.|   |..|           |.....||......||...|.:.|..|...
 Frog   689 SLL---------AAVAL---GSDLSEMVPQEEKRKGIFQWAGRGPRRRTSSPSRPMSYGEESVIP 741

  Fly   814 PNQLTLPSEDNNTYDHAFYRDVIKKMSMASSERVNSKSSGDLTMYNSSTPLTARDC--DDAEEAF 876
            .:.:||.|              :..:|..:|.|...:|..|....:|.|..|.|..  |..::..
 Frog   742 SSSVTLIS--------------LSSISDCNSTRSLIRSDSDDIGLDSDTMSTGRVVKEDRGQQPN 792

  Fly   877 EGGR---------FQRNFSGSQFPRHCFFTR---QEEEGEAE-DEDAVAAEV------DTADADA 922
            .|..         |:|:...|..|.|....|   .|..|... ..|....:|      ..:|..|
 Frog   793 VGTNPLVDYKVESFKRDPKQSLTPTHVTAGRNNTNETRGHRRTPSDGAIRQVTQGHKRSPSDGSA 857

  Fly   923 DDECQVPASQMRQNSTTSRKSSVTF--------QSVSFEEP---DFVATPRTTARSDLYTSSASI 976
            ..:|: |.|  ::.|...|.....|        :....|.|   :|...||.::..........:
 Frog   858 PFQCE-PGS--KEPSPFPRLPDPHFVFPPPVRRKDTGVERPTSLEFAPRPRPSSSRPRMDPWKFV 919

  Fly   977 SFATYRSASPSLSSSSTTASAS---PSIASTE 1005
            |.:...|:|||.......:|.|   |.:|..|
 Frog   920 SLSQTHSSSPSSGGGDACSSGSAEGPRVAEVE 951

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	36/56 (64%)
		STKc_MLK	134..389	CDD:270963	163/256 (64%)
map3k10	XP_002938858.3	SH3_MLK1-3	37..94	CDD:212992	36/56 (64%)
		STKc_MLK2	124..381	CDD:271050	163/256 (64%)