DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mgstl and Ptges

DIOPT Version :9

Sequence 1:	NP_524696.2	Gene:	Mgstl / 44110	FlyBaseID:	FBgn0025814	Length:	152	Species:	Drosophila melanogaster
Sequence 2:	NP_071860.1	Gene:	Ptges / 64292	MGIID:	1927593	Length:	153	Species:	Mus musculus

Alignment Length:	152	Identity:	58/152 - (38%)
Similarity:	82/152 - (53%)	Gaps:	3/152 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASPVELLSLSNPVFKSFTFWVGVLVIKMLLMSLLTAIQRFKTKTFANPED-LMSPKLKVKFDDP 64
            |.|| .|:..|..|..:|.....:|||||..::::|...|.:.|.|||||| |....|:....||
Mouse     1 MPSP-GLVMESGQVLPAFLLCSTLLVIKMYAVAVITGQMRLRKKAFANPEDALKRGGLQYYRSDP 64

  Fly    65 NVERVRRAHRNDLENILPFFAIGLLYVLTDPAAFLAINLFRAVGIARIVHTLVYAVVVVPQPSRA 129
            :|||..||||||:|.|.||..:|.:|....|...:|...|..|...|:|||:.|...:.|: .|:
Mouse    65 DVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPLIAWIHFLVVLTGRVVHTVAYLGKLNPR-LRS 128

  Fly   130 LAFFVALGATVYMALQVIASAA 151
            .|:.:|..:...||||::...|
Mouse   129 GAYVLAQFSCFSMALQILWEVA 150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mgstl	NP_524696.2	MAPEG	20..148	CDD:395893	50/128 (39%)
Ptges	NP_071860.1	MAPEG	17..147	CDD:376462	51/130 (39%)
		Glutathione binding. /evidence=ECO:0000250\|UniProtKB:O14684	74..78		3/3 (100%)
		Glutathione binding. /evidence=ECO:0000250\|UniProtKB:O14684	127..131		1/3 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836765
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2B1WH
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG50114
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10689
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.810