DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mgstl and Ptges

DIOPT Version :9

Sequence 1:	NP_524696.2	Gene:	Mgstl / 44110	FlyBaseID:	FBgn0025814	Length:	152	Species:	Drosophila melanogaster
Sequence 2:	NP_067594.1	Gene:	Ptges / 59103	RGDID:	62076	Length:	153	Species:	Rattus norvegicus

Alignment Length:	146	Identity:	55/146 - (37%)
Similarity:	80/146 - (54%)	Gaps:	2/146 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLSLSNPVFKSFTFWVGVLVIKMLLMSLLTAIQRFKTKTFANPED-LMSPKLKVKFDDPNVERVR 70
            |:..::.|..:|.....:|||||..::::|...|.:.|.|||||| |....|:....||:|||..
  Rat     6 LVMENSQVLPAFLLCSTLLVIKMYAVAVITGQVRLRKKAFANPEDALKRGGLQYCRSDPDVERCL 70

  Fly    71 RAHRNDLENILPFFAIGLLYVLTDPAAFLAINLFRAVGIARIVHTLVYAVVVVPQPSRALAFFVA 135
            ||||||:|.|.||..:|.:|....|...:|...|..|...|:|||:.|...:.|: .|:.|:.:|
  Rat    71 RAHRNDMETIYPFLFLGFVYSFLGPNPLIAWIHFLVVLTGRVVHTVAYLGKMNPR-IRSGAYVLA 134

  Fly   136 LGATVYMALQVIASAA 151
            ..|...||||::...|
  Rat   135 QFACFSMALQILWEVA 150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mgstl	NP_524696.2	MAPEG	20..148	CDD:395893	51/128 (40%)
Ptges	NP_067594.1	MAPEG	17..147	CDD:395893	52/130 (40%)
		Glutathione binding. /evidence=ECO:0000250\|UniProtKB:O14684	74..78		3/3 (100%)
		Glutathione binding. /evidence=ECO:0000250\|UniProtKB:O14684	127..131		1/3 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340469
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2B1WH
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG50114
OrthoDB	1	1.010	-	-		D1591261at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10689
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860