Protein Alignment Optix and six4b

DIOPT Version :9

• Sequence 1: NP_001260793.1
• Gene: Optix / 44108
• FlyBaseID: FBgn0025360
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_571792.2
• Gene: six4b / 65232
• ZFINID: ZDB-GENE-010201-1
• Length: 615
• Species: Danio rerio
• Alignment Length: 496
• Identity: 159/496 - (32%)
• Similarity: 219/496 - (44%)
• Gaps: 114/496 - (22%)

  Fly    34 TLAFSAAQVEIVCKTLEDSGDIERLARFLWSLPVALPNMHEIL-NCEAVLRARAVVAYHVGNFRE 97
            :||||..||..||:.|...|:::||||||||||     ..::| ..|::|:|:|:||:|...::|
Zfish    62 SLAFSPEQVACVCEALMQGGNVDRLARFLWSLP-----QSDLLRGNESILKAQAIVAFHHARYQE 121

  Fly    98 LYAIIENHKFTKASYGKLQAMWLEAHYIEAEKLRGRSLGPVDKYRVRKKFPLPPTIWDGEQKTHC 162
            ||.|:|||.|:.:::..||.||.:|.|.||||.|||.||.|||||:|:|:|||.||||||:..:|
Zfish   122 LYCILENHSFSPSNHSSLQDMWYKARYTEAEKARGRPLGAVDKYRLRRKYPLPRTIWDGEETVYC 186

  Fly   163 FKERTRSLLREWYLQDPYPNPTKKRELAKATGLNPTQVGNWFKNRRQRDRAAAAKNRIQHSQNSS 227
            ||||:|:.|::.|.::.||:|.:||.|||.|||:.|||.|||||||||||..:.......|..:.
Zfish   187 FKERSRNALKDMYKRNRYPSPAEKRNLAKMTGLSLTQVSNWFKNRRQRDRNPSEAQSKSESDGNH 251

  Fly   228 GMGCRSRRADGAASPTP-SDSSDSDISLGTHSP------------------VPSSLQLQHSPGST 273
            .....|.:.....||.| |..|.|.:..||..|                  :||     ||.|..
Zfish   252 STEDESSKGQEDLSPRPLSSGSSSSVPHGTAPPTVYSDGGTTVIQQIGDVKMPS-----HSGGGM 311

  Fly   274 S--------------NGANDREES---------------LSVDDDK------PRDLSGS----LP 299
            |              :||.....|               |:.|..:      .|.|.||    .|
Zfish   312 SYNGDLASVNAHYINSGAYGHSHSSNALLNGLGATGGHFLTFDPQRVSHHSQERLLGGSSVSYAP 376

  Fly   300 LPLSLPLPLASPTHTPPQLPPGYGGGA-------GAGPGGPLTGPGCLPPFKLDAATSLFSAGCY 357
            ..:.:....:....|...|......|.       .:.|..|.|..|                |.:
Zfish   377 FSMGVSETASGKIDTMQTLVSNGEDGVISSVVSFASAPSTPSTTSG----------------GLH 425

  Fly   358 LQSFS--NLKEMSQQFPIQPIVLRP------HPQLPQSLALNGASGGPPLHHPAYAAAYSVEC-- 412
            |.|:|  ||........:.|::|.|      |...|....::.:|     .|.:....||...
Zfish   426 LSSYSVVNLPGNESTMGLPPLMLPPSSTSSTHGSAPLGNVVSDSS-----QHSSQTLLYSQTVKQ 485

  Fly   413 ----VPGGHGPPHPPPKLRINSPEKLNSTAVAAAASVGGGG 449
                |||.:..|...|   ::....|..||....:|....|
Zfish   486 EPLDVPGSYAYPSDMP---LDQGSNLGYTASLFLSSSSSSG 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Optix	NP_001260793.1	SIX1_SD	37..150	CDD:293483	57/113 (50%)
		homeodomain	158..206	CDD:238039	25/47 (53%)
six4b	NP_571792.2	SIX1_SD	65..174	CDD:293483	57/113 (50%)
		homeodomain	185..239	CDD:238039	33/53 (62%)
		E_Pc_C	<395..>478	CDD:284226	19/103 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593953
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0775
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740