Protein Alignment Optix and ANHX

DIOPT Version :9

• Sequence 1: NP_001260793.1
• Gene: Optix / 44108
• FlyBaseID: FBgn0025360
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: XP_006719806.1
• Gene: ANHX / 647589
• HGNCID: 40024
• Length: 492
• Species: Homo sapiens
• Alignment Length: 445
• Identity: 114/445 - (25%)
• Similarity: 176/445 - (39%)
• Gaps: 71/445 - (15%)

  Fly    20 HHQIIAPSPILAVPTLAFSAAQVEIVCKTLEDSGDIERLARFLWSLPVALPNMHEILNCEAVLRA 84
            |....||...|.  |||..      :|:..:|  |:.:|...:.::..:...:|.:.|.:..| |
Human    11 HEDTCAPPAELV--TLAGR------LCRDFQD--DLAQLQPLVTAILDSQLRLHLLDNADVAL-A 64

  Fly    85 RAVVAYHVGNFRELYAIIENHKFTKASYGKLQAMWLEAHY-IEAEKLRGRSLGPVDKYRVRKKFP 148
            .|.|.......:....::|..:....|. :|..:|.:.|| :...:|...:|.||.|:|.||:.|
Human    65 CARVLDQQEQQQAACRLLEGCQVPGGSQ-ELVQLWNDIHYRLVMRRLGVAALTPVQKFRCRKRNP 128

  Fly   149 LPPTIWDGEQKTHCFKERTRSLLREWYL-QDPYPNPTKKRELAKATGLNPTQVGNWFKNRRQRDR 212
            .||::.....|:..|....|..|..:.: .:..|:..::..||..|.|.|.||.|||.|.|:|.|
Human   129 PPPSLCPEGLKSRNFPREVREKLHNFAVGVNTNPSKAERENLALETSLTPEQVYNWFANYRRRQR 193

  Fly   213 AAAAKNRIQHSQNSSGMGCRSRRADGAASPTPSDSSDSDISLGTHSPVPSSLQLQHSPGSTSNGA 277
            |.....:......:...|.|.|..| ...|:.:...||..   ...|..|..:.:..|..:....
Human   194 ALPQHMKPAQQATAEDPGARERGPD-LLQPSGNPRVDSGF---VDRPQWSEEREEKGPPQSPQTT 254

  Fly   278 NDREESLSVDDDKPRDLSGSLPLPL-SLP---LPLASPTHTPPQLP---PGYGGGAGAGPG-GPL 334
            ....|.|::..|.|.|.:.|.||.: |||   :....|.|.|..||   |        ||| .||
Human   255 QGPWEPLALAPDFPADETVSKPLDVRSLPGGEMYQEGPGHDPATLPLFCP--------GPGLCPL 311

  Fly   335 -TGPGCLPPFKLDAATSLFSAGCYLQS--FSNLKEMSQQ-----------FPIQP---------- 375
             .|...|.|       ||.:...:|.|  .::.||:|.|           |.:.|
Human   312 AAGNDMLNP-------SLAAPESWLMSLALASSKEVSFQTGQLVHSHGLDFMMGPADTAVAVSIA 369

  Fly   376 IVLRPHPQLPQSLALNGASGGPPLHHPAYAAAYSVECVPGGHGPPHPPPKLRINS 430
            .:..|.|.:.:.::|:....|||..||     .||: :..|.|......:||:.|
Human   370 TLGDPSPTVCRGISLHAGFSGPPSGHP-----QSVQ-LEEGLGTSSGRTELRVGS 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Optix	NP_001260793.1	SIX1_SD	37..150	CDD:293483	25/113 (22%)
		homeodomain	158..206	CDD:238039	15/48 (31%)
ANHX	XP_006719806.1	SIX1_SD	<79..130	CDD:293483	15/51 (29%)
		homeodomain	139..193	CDD:238039	18/53 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158079
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0775
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10390
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840