Protein Alignment Optix and six2b

DIOPT Version :9

• Sequence 1: NP_001260793.1
• Gene: Optix / 44108
• FlyBaseID: FBgn0025360
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001122206.1
• Gene: six2b / 566454
• ZFINID: ZDB-GENE-080723-23
• Length: 285
• Species: Danio rerio
• Alignment Length: 298
• Identity: 139/298 - (46%)
• Similarity: 183/298 - (61%)
• Gaps: 60/298 - (20%)

  Fly    33 PTLAFSAAQVEIVCKTLEDSGDIERLARFLWSLPVALPNMHEILNCEAVLRARAVVAYHVGNFRE 97
            ||..|:..||..||:.|:..|.||||.||||||| |..::|:   .|:||:|:||||:|.|||||
Zfish     5 PTFGFTQEQVACVCEVLQQGGSIERLGRFLWSLP-ACEHLHK---NESVLKAKAVVAFHRGNFRE 65

  Fly    98 LYAIIENHKFTKASYGKLQAMWLEAHYIEAEKLRGRSLGPVDKYRVRKKFPLPPTIWDGEQKTHC 162
            ||.::|:|:|:..::.|||.:||:||||||||||||.||.|.|||||:|||||.:|||||:.::|
Zfish    66 LYKVLESHQFSPHNHPKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETSYC 130

  Fly   163 FKERTRSLLREWYLQDPYPNPTKKRELAKATGLNPTQVGNWFKNRRQRDRAAAAKNRIQHSQNSS 227
            |||::|.:|:|||..:|||:|.:|||||:||||..|||.|||||||||||||.||.|.....|.:
Zfish   131 FKEKSRCVLKEWYTHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENEGANPN 195

  Fly   228 GMGCRSRRADGAASPTPSDSSDSDISLGTHSPVPSSLQLQHSPGSTSNGANDREESL--SVDDDK 290
            |                            |:|:.|.:              :..:||  |.||||
Zfish   196 G----------------------------HNPLTSHV--------------NENKSLCESSDDDK 218

  Fly   291 P-------RDLSGSLPLPLSLPLPLASPTHT--PPQLP 319
            .       .::|.::.:|.|..||   |.|:  ||..|
Zfish   219 SPAGTPDHTNMSPAILMPSSSGLP---PLHSFAPPPGP 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Optix	NP_001260793.1	SIX1_SD	37..150	CDD:293483	67/112 (60%)
		homeodomain	158..206	CDD:238039	28/47 (60%)
six2b	NP_001122206.1	SIX1_SD	9..118	CDD:293483	67/112 (60%)
		homeodomain	129..180	CDD:238039	34/50 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593946
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0775
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X333
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740