Protein Alignment Optix and six6b

DIOPT Version :10

• Sequence 1: NP_001260793.1
• Gene: Optix / 44108
• FlyBaseID: FBgn0025360
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001018421.1
• Gene: six6b / 553611
• ZFINID: ZDB-GENE-050522-308
• Length: 245
• Species: Danio rerio
• Alignment Length: 251
• Identity: 168/251 - (66%)
• Similarity: 189/251 - (75%)
• Gaps: 13/251 - (5%)

  Fly    32 VPTLAFSAAQVEIVCKTLEDSGDIERLARFLWSLPVALPNMHEILN-CEAVLRARAVVAYHVGNF 95
            :|.|.||..||..||:|||:|||||||.||||||||| |...|:|| .|:||||||:||:|.|||
Zfish     4 LPILNFSPQQVAGVCETLEESGDIERLGRFLWSLPVA-PAACEVLNRNESVLRARAIVAFHTGNF 67

  Fly    96 RELYAIIENHKFTKASYGKLQAMWLEAHYIEAEKLRGRSLGPVDKYRVRKKFPLPPTIWDGEQKT 160
            ||||.|:|||||||.|:.||||:|||:||.||||||||.||||||||||||||||.|||||||||
Zfish    68 RELYHILENHKFTKESHSKLQALWLESHYQEAEKLRGRPLGPVDKYRVRKKFPLPKTIWDGEQKT 132

  Fly   161 HCFKERTRSLLREWYLQDPYPNPTKKRELAKATGLNPTQVGNWFKNRRQRDRAAAAKNRIQHSQN 225
            ||||||||.||||||||||||||:||||||:||||.|||||||||||||||||||||||:|....
Zfish   133 HCFKERTRHLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQQQVL 197

  Fly   226 SSGMGCRSRRADGAASPTPSDSSDSDISLGTHSPVPSSLQLQHSPGSTSNGANDRE 281
            |:|........|||..           .||..|...:||..:.:..:.|..::|.|
Zfish   198 SNGSVRSLSGEDGAVD-----------RLGNASSPEASLSSKAAASAISITSSDSE 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Optix	NP_001260793.1	SIX1_SD	37..150	CDD:465293	86/113 (76%)
		homeodomain	158..206	CDD:238039	43/47 (91%)
six6b	NP_001018421.1	SIX1_SD	9..122	CDD:465293	86/113 (76%)
		homeodomain	130..178	CDD:238039	43/47 (91%)