Protein Alignment Optix and six1a

DIOPT Version :10

• Sequence 1: NP_001260793.1
• Gene: Optix / 44108
• FlyBaseID: FBgn0025360
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001009904.1
• Gene: six1a / 494168
• ZFINID: ZDB-GENE-040718-155
• Length: 283
• Species: Danio rerio
• Alignment Length: 294
• Identity: 141/294 - (47%)
• Similarity: 191/294 - (64%)
• Gaps: 38/294 - (12%)

  Fly    32 VPTLAFSAAQVEIVCKTLEDSGDIERLARFLWSLPVALPNMHEILNCEAVLRARAVVAYHVGNFR 96
            :|:..|:..||..||:.|:..|::|||.||||||| |..::|:   .|:||:|:||||:|.||||
Zfish     4 LPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLP-ACDHLHK---NESVLKAKAVVAFHRGNFR 64

  Fly    97 ELYAIIENHKFTKASYGKLQAMWLEAHYIEAEKLRGRSLGPVDKYRVRKKFPLPPTIWDGEQKTH 161
            |||.|:|:::|:..::.|:|.:||:|||:||||||||.||.|.|||||:|||||.||||||:.::
Zfish    65 ELYKILESYQFSTHNHPKMQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSY 129

  Fly   162 CFKERTRSLLREWYLQDPYPNPTKKRELAKATGLNPTQVGNWFKNRRQRDRAAAAKNRIQHSQNS 226
            ||||::||:|||||..:|||:|.:|||||:||||..|||.|||||||||||||.||.| ::.:|:
Zfish   130 CFKEKSRSVLREWYTHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER-ENGENN 193

  Fly   227 SGMGCRSRRA--DGAASPTPSDSSDSDISLGTHSPVPSSLQL----QHSPGSTSNGANDREESLS 285
            ...|.:|:|:  ||..|..   ||..|......||..||:.|    .::||:.
Zfish   194 GVGGKQSQRSPLDGVKSLM---SSSEDEFSPPQSPEHSSVLLLQGTMNNPGAP------------ 243

  Fly   286 VDDDKPRDLSGSLPLP-LSLPLPLASPTHTPPQL 318
                       :.|:| |..|.||......|.|:
Zfish   244 -----------AYPMPGLGAPHPLHGMQGHPHQI 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Optix	NP_001260793.1	SIX1_SD	37..150	CDD:465293	64/112 (57%)
		homeodomain	158..206	CDD:238039	30/47 (64%)
six1a	NP_001009904.1	SIX1_SD	9..118	CDD:465293	64/112 (57%)
		homeodomain	129..180	CDD:238039	36/50 (72%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	168..264		40/122 (33%)