Protein Alignment Optix and six1b

DIOPT Version :9

• Sequence 1: NP_001260793.1
• Gene: Optix / 44108
• FlyBaseID: FBgn0025360
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_996978.1
• Gene: six1b / 404627
• ZFINID: ZDB-GENE-040426-2308
• Length: 284
• Species: Danio rerio
• Alignment Length: 283
• Identity: 141/283 - (49%)
• Similarity: 187/283 - (66%)
• Gaps: 15/283 - (5%)

  Fly    32 VPTLAFSAAQVEIVCKTLEDSGDIERLARFLWSLPVALPNMHEILNCEAVLRARAVVAYHVGNFR 96
            :|:..|:..||..||:.|:..|::|||.||||||| |..::|:   .|:||:|:||||:|.||||
Zfish     4 LPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLP-ACDHLHK---NESVLKAKAVVAFHRGNFR 64

  Fly    97 ELYAIIENHKFTKASYGKLQAMWLEAHYIEAEKLRGRSLGPVDKYRVRKKFPLPPTIWDGEQKTH 161
            |||.|:|:|:|:..::.|||.:||:||||||||||||.||.|.|||||:|||||.||||||:.::
Zfish    65 ELYKILESHQFSPHNHPKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSY 129

  Fly   162 CFKERTRSLLREWYLQDPYPNPTKKRELAKATGLNPTQVGNWFKNRRQRDRAAAAKNRIQHSQNS 226
            ||||::|.:|||||..:|||:|.:|||||:||||..|||.|||||||||||||.||.|.....|:
Zfish   130 CFKEKSRGVLREWYTHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENSENNN 194

  Fly   227 SGMGCRSRRA--DGAASPTPSDSSDSDISLGTHSPVPSSLQL----QHSPGSTSNGANDREESLS 285
            :|...:::.:  ||..|..   ||..|......||..:|:.|    ...||:::........:.|
Zfish   195 TGANKQNQLSPLDGGKSLM---SSSEDEFSPPQSPDQNSVLLLQGNMSHPGASAYSMTGLGAAQS 256

  Fly   286 VD--DDKPRDLSGSLPLPLSLPL 306
            |.  ...|..|..||..||:..|
Zfish   257 VHGMQGHPHQLQDSLLGPLTSSL 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Optix	NP_001260793.1	SIX1_SD	37..150	CDD:293483	67/112 (60%)
		homeodomain	158..206	CDD:238039	29/47 (62%)
six1b	NP_996978.1	SIX1_SD	9..118	CDD:407119	67/112 (60%)
		homeodomain	129..180	CDD:238039	35/50 (70%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	167..238		30/73 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0775
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X333
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810