Protein Alignment Optix and Six6

DIOPT Version :9

• Sequence 1: NP_001260793.1
• Gene: Optix / 44108
• FlyBaseID: FBgn0025360
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_035514.1
• Gene: Six6 / 20476
• MGIID: 1341840
• Length: 246
• Species: Mus musculus
• Alignment Length: 251
• Identity: 169/251 - (67%)
• Similarity: 192/251 - (76%)
• Gaps: 12/251 - (4%)

  Fly    32 VPTLAFSAAQVEIVCKTLEDSGDIERLARFLWSLPVALPNMHEILN-CEAVLRARAVVAYHVGNF 95
            :|.|.||..||..||:|||:|||:|||.||||||||| |...|.|| .|:||||||:||:|.||:
Mouse     4 LPILNFSPQQVAGVCETLEESGDVERLGRFLWSLPVA-PAACEALNKNESVLRARAIVAFHGGNY 67

  Fly    96 RELYAIIENHKFTKASYGKLQAMWLEAHYIEAEKLRGRSLGPVDKYRVRKKFPLPPTIWDGEQKT 160
            ||||.|:|||||||.|:.||||:||||||.||||||||.||||||||||||||||.|||||||||
Mouse    68 RELYHILENHKFTKESHAKLQALWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKT 132

  Fly   161 HCFKERTRSLLREWYLQDPYPNPTKKRELAKATGLNPTQVGNWFKNRRQRDRAAAAKNRIQHSQN 225
            ||||||||.||||||||||||||:||||||:||||.|||||||||||||||||||||||:|....
Mouse   133 HCFKERTRHLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQQQVL 197

  Fly   226 SSGMGCRSRRADGAASPTPSDSSDSDISLGTHSPVPSSLQLQHSPGSTSNGANDRE 281
            |.|.| |..|::|..:|.         .||..|...:||..:.:..:.|..::|.|
Mouse   198 SQGPG-RVLRSEGEGTPE---------VLGVASSPAASLSSKAATSAISITSSDSE 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Optix	NP_001260793.1	SIX1_SD	37..150	CDD:293483	85/113 (75%)
		homeodomain	158..206	CDD:238039	43/47 (91%)
Six6	NP_035514.1	SIX1_SD	9..122	CDD:407119	85/113 (75%)
		homeodomain	130..178	CDD:238039	43/47 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..246		18/64 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848462
Domainoid	1	1.000	175	1.000	Domainoid score	I3634
eggNOG	1	0.900	-	-		E1_KOG0775
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	1.000	Inparanoid score	I2501
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002292
OrthoInspector	1	1.000	-	-		otm43673
orthoMCL	1	0.900	-	-		OOG6_105562
Panther	1	1.100	-	-	LDO	PTHR10390
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2573
SonicParanoid	1	1.000	-	-		X333
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.780