Protein Alignment Optix and Six2

DIOPT Version :9

• Sequence 1: NP_001260793.1
• Gene: Optix / 44108
• FlyBaseID: FBgn0025360
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: XP_006523994.1
• Gene: Six2 / 20472
• MGIID: 102778
• Length: 298
• Species: Mus musculus
• Alignment Length: 319
• Identity: 151/319 - (47%)
• Similarity: 196/319 - (61%)
• Gaps: 52/319 - (16%)

  Fly    32 VPTLAFSAAQVEIVCKTLEDSGDIERLARFLWSLPVALPNMHEILNCEAVLRARAVVAYHVGNFR 96
            :||..|:..||..||:.|:..|:||||.||||||| |..::|:   .|:||:|:||||:|.||||
Mouse     4 LPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLP-ACEHLHK---NESVLKAKAVVAFHRGNFR 64

  Fly    97 ELYAIIENHKFTKASYGKLQAMWLEAHYIEAEKLRGRSLGPVDKYRVRKKFPLPPTIWDGEQKTH 161
            |||.|:|:|:|:..::.|||.:||:||||||||||||.||.|.|||||:|||||.:|||||:.::
Mouse    65 ELYKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETSY 129

  Fly   162 CFKERTRSLLREWYLQDPYPNPTKKRELAKATGLNPTQVGNWFKNRRQRDRAAAAKNRIQHSQNS 226
            ||||::||:|||||..:|||:|.:|||||:||||..|||.|||||||||||||.||.|.:.:
Mouse   130 CFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERYEEN--- 191

  Fly   227 SGMGCRSRRADGAASPTPSDSSDSDISLGTHSPVPSSLQLQHSPGSTSNGANDREESLSVDDDKP 291
                              |::|:|    .:|:|:.|||          ||:.......|.|:..|
Mouse   192 ------------------SENSNS----SSHNPLASSL----------NGSGKSVLGSSEDEKTP 224

  Fly   292 R---DLSGSLPLPLSLPLPLASPTHTPPQLPPGYGGGAGAGPGG---PLTGPGCLPPFK 344
            .   |.|.|.|..|..|.|       ||.||..:..|...||..   |:.|.|...|.:
Mouse   225 SGTPDHSSSSPALLLSPPP-------PPGLPSLHSLGHPPGPSAVPVPVPGGGGADPLQ 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Optix	NP_001260793.1	SIX1_SD	37..150	CDD:293483	68/112 (61%)
		homeodomain	158..206	CDD:238039	30/47 (64%)
Six2	XP_006523994.1	SIX1_SD	9..118	CDD:407119	68/112 (61%)
		homeodomain	129..180	CDD:238039	36/50 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848463
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0775
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X333
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740