Protein Alignment Optix and unc-39

DIOPT Version :9

• Sequence 1: NP_001260793.1
• Gene: Optix / 44108
• FlyBaseID: FBgn0025360
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_506563.2
• Gene: unc-39 / 191623
• WormBaseID: WBGene00006775
• Length: 335
• Species: Caenorhabditis elegans
• Alignment Length: 303
• Identity: 94/303 - (31%)
• Similarity: 141/303 - (46%)
• Gaps: 58/303 - (19%)

  Fly    11 PPSESFSPTHHQIIAPSPILAVPTLA--------------------FSAAQVEIVCKTLEDSGDI 55
            ||.|..|    .|:.||.::..|:.:                    :|..|:|.:..:|..:.|.
 Worm    55 PPYELSS----HILTPSSVIPTPSPSVASASISSPTIPAFGCTMSEYSMEQMEAISTSLFQARDG 115

  Fly    56 ERLARFLWSLPVAL-PNMHEILNCEAVLRARAVVAYHVGNFRELYAIIENHKFTKASYGKLQAMW 119
            :||..|...|.... ||..:.|..||::.|.....||...|..|:.::.|..|.:..|..||.:|
 Worm   116 DRLVAFFKQLESLYGPNAVDHLRSEAIIVAYTYALYHSNEFETLFHLLSNRHFQQRHYNDLQDIW 180

  Fly   120 LEAHYIEAEKLRGRSLGPVDKYRVRKKFPLPPTIWDGEQKTHCFKERTRSLLREWYLQ-DPYPNP 183
            ..|.|.|::..||:.|.||:|||:|:|||.|.||||||:..:.||:.:|..|::::.. ..||..
 Worm   181 HHARYKESQLKRGKELNPVEKYRLRRKFPAPKTIWDGEEIVYSFKDSSRKFLKQFFRNVSEYPTQ 245

  Fly   184 TKKRELAKATGLNPTQVGNWFKNRRQRDRAAAAKNRIQHSQNSSGMGCRSRRADGAASPTPSDSS 248
            .:|||:::||||...|:.||||||||||:          |.||             |..:|..||
 Worm   246 EQKREISRATGLKIVQISNWFKNRRQRDK----------SNNS-------------AKCSPPSSS 287

  Fly   249 DSDISLGTHSPV--PSSLQLQHSP-------GSTSNGANDREE 282
            .|........|:  |.|..|..:|       |:..:..:|.::
 Worm   288 SSTNGGSDFLPIITPQSFNLAAAPFNMNMIYGTLRDSQSDNDQ 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Optix	NP_001260793.1	SIX1_SD	37..150	CDD:293483	40/113 (35%)
		homeodomain	158..206	CDD:238039	17/48 (35%)
unc-39	NP_506563.2	SIX1_SD	97..211	CDD:293483	40/113 (35%)
		homeodomain	222..277	CDD:238039	25/64 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0775
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810