Protein Alignment Optix and six3

DIOPT Version :10

• Sequence 1: NP_001260793.1
• Gene: Optix / 44108
• FlyBaseID: FBgn0025360
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: XP_002944388.2
• Gene: six3 / 100493798
• XenbaseID: XB-GENE-478761
• Length: 295
• Species: Xenopus tropicalis
• Alignment Length: 230
• Identity: 171/230 - (74%)
• Similarity: 188/230 - (81%)
• Gaps: 14/230 - (6%)

  Fly    32 VPTLAFSAAQVEIVCKTLEDSGDIERLARFLWSLPVALPNMHEILN-CEAVLRARAVVAYHVGNF 95
            :|:|.||..||..||:|||::||||||.||||||||| |...|.:| .|::||||||||:|.|||
 Frog    44 LPSLNFSPEQVASVCETLEETGDIERLGRFLWSLPVA-PGACEAINKHESILRARAVVAFHTGNF 107

  Fly    96 RELYAIIENHKFTKASYGKLQAMWLEAHYIEAEKLRGRSLGPVDKYRVRKKFPLPPTIWDGEQKT 160
            |:||.|:|||||||.|:||||||||||||.||||||||.||||||||||||||||.|||||||||
 Frog   108 RDLYHILENHKFTKESHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKT 172

  Fly   161 HCFKERTRSLLREWYLQDPYPNPTKKRELAKATGLNPTQVGNWFKNRRQRDRAAAAKNRIQH-SQ 224
            |||||||||||||||||||||||:||||||:||||.|||||||||||||||||||||||:|| |.
 Frog   173 HCFKERTRSLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHQSI 237

  Fly   225 NSSGM------GCRSRR-----ADGAASPTPSDSS 248
            ..|||      ||.:..     :..|||||.|.||
 Frog   238 GQSGMRSLADPGCPTHSSAESPSTAAASPTTSVSS 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Optix	NP_001260793.1	SIX1_SD	37..150	CDD:465293	86/113 (76%)
		homeodomain	158..206	CDD:238039	44/47 (94%)
six3	XP_002944388.2	SIX1_SD	49..162	CDD:465293	86/113 (76%)
		homeodomain	170..218	CDD:238039	44/47 (94%)