Protein Alignment Optix and six2

DIOPT Version :9

• Sequence 1: NP_001260793.1
• Gene: Optix / 44108
• FlyBaseID: FBgn0025360
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001093745.1
• Gene: six2 / 100101784
• XenbaseID: XB-GENE-481504
• Length: 289
• Species: Xenopus tropicalis
• Alignment Length: 371
• Identity: 152/371 - (40%)
• Similarity: 206/371 - (55%)
• Gaps: 106/371 - (28%)

  Fly    32 VPTLAFSAAQVEIVCKTLEDSGDIERLARFLWSLPVALPNMHEILNCEAVLRARAVVAYHVGNFR 96
            :||..|:..||..||:.|:..|:||||.||||||| |..::|:   .|:||:|:||||:|.||||
 Frog     4 LPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLP-ACEHLHK---NESVLKAKAVVAFHRGNFR 64

  Fly    97 ELYAIIENHKFTKASYGKLQAMWLEAHYIEAEKLRGRSLGPVDKYRVRKKFPLPPTIWDGEQKTH 161
            |||.|:|.|:|:..::.|||.:||:||||||||||||.||.|.|||||:|||||.:|||||:.::
 Frog    65 ELYKILEGHQFSPHNHPKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETSY 129

  Fly   162 CFKERTRSLLREWYLQDPYPNPTKKRELAKATGLNPTQVGNWFKNRRQRDRAAAAKNRIQHSQNS 226
            ||||::||:|||||..:|||:|.:|||||:||||..|||.|||||||||||||.||.|.:.:
 Frog   130 CFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERYEEN--- 191

  Fly   227 SGMGCRSRRADGAASPTPSDSSDSDISLGTHSPVPSSLQLQHSPGSTSNGANDREESLSVDDDKP 291
                              :::|:|:    :|:|:.:|:    :.|.|..|        |.||||
 Frog   192 ------------------NENSNSN----SHNPLSTSM----NGGKTVLG--------SSDDDK- 221

  Fly   292 RDLSGSLPLPLSLPLPLASPTHTPPQLPPGYGGGAGAGPGGPLTG-PGCLPPFKLDAATSLFSAG 355
                          .|..:|.||            .:.|...|:| ||
 Frog   222 --------------TPSGTPDHT------------SSSPALLLSGNPG----------------- 243

  Fly   356 CYLQSFSNLKEMSQQFPIQPIVLRPHPQLPQSLALNGASGGPPLHH 401
              ||:...:.               |||.|.::.::.|.   |:||
 Frog   244 --LQALHGMS---------------HPQGPSAIPVSAAD---PMHH 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Optix	NP_001260793.1	SIX1_SD	37..150	CDD:293483	68/112 (61%)
		homeodomain	158..206	CDD:238039	30/47 (64%)
six2	NP_001093745.1	SIX1_SD	9..118	CDD:374862	68/112 (61%)
		homeodomain	129..180	CDD:238039	36/50 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X333
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000