Protein Alignment Patj and PDZD3

DIOPT Version :9

• Sequence 1: NP_477342.1
• Gene: Patj / 44100
• FlyBaseID: FBgn0067864
• Length: 871
• Species: Drosophila melanogaster
• Sequence 2: XP_011541302.1
• Gene: PDZD3 / 79849
• HGNCID: 19891
• Length: 571
• Species: Homo sapiens
• Alignment Length: 651
• Identity: 126/651 - (19%)
• Similarity: 200/651 - (30%)
• Gaps: 260/651 - (39%)

  Fly     2 HLSADISSALQQI-------EAVKKGIDESDDPKLQMQTAESLSTILGILQDPVFRTIVHVQDSL 59
            ||..::..|...:       .|.::|:.|.|             .||.:..|     :|..:|..
Human   129 HLQQELGRAGHVVCRVDPGTSAQRQGLQEGD-------------RILAVNND-----VVEHEDYA 175

  Fly    60 SELNAQLAQHPSMLPNDFDIDVAGNLVLSLNGGEVMYDFDEQRSSSHSHSAPGSPDKSGGVGEEP 124
            ..:....|..|.:|..          ||:.:.    :|....:....:|..|     :.|.|..|
Human   176 VVVRRIRASSPRVLLT----------VLARHA----HDVARAQLGEDAHLCP-----TLGPGVRP 221

  Fly   125 RPQSQNSKGAGVADLYATDYAQIQAIELVNDGTGLGFGIIGARNSGVIVKTILPGGVADKDGRLR 189
            |                       ...:|.|..|.||.:... |.|.....:..||.|::.| :.
Human   222 R-----------------------LCHIVKDEGGFGFSVTHG-NQGPFWLVLSTGGAAERAG-VP 261

  Fly   190 SGDHILQIGDVNLHEMVSEQVAAVLRQSGTHVRLVVARPVEQSVPTPQYALEPGTAVVPTRVLVD 254
            .|..:|::..|::.:....|:...|.|||..|.|:||.|
Human   262 PGARLLEVNGVSVEKFTHNQLTRKLWQSGQQVTLLVAGP-------------------------- 300

  Fly   255 PAELERYLISTGYPEIFGESSTASTPQTTTEDDRFVYRGETSMLIDPNIDLEELLALPETEKLQV 319
              |:|......|.|                             |..|   |.|..||| |:...:
Human   301 --EVEEQCRQLGLP-----------------------------LAAP---LAEGWALP-TKPRCL 330

  Fly   320 ELKKDANGLGITIAGYVCEKEELS---GIFVKSVSPGSAADLSGRIRVNDRIIEVDGQSLQGYSN 381
            .|:|...|.|..:.    |::.|.   |.|:..|.||..|..:| ::..||::.|.|:|::|..:
Human   331 HLEKGPQGFGFLLR----EEKGLDGRPGQFLWEVDPGLPAKKAG-MQAGDRLVAVAGESVEGLGH 390

  Fly   382 HQAVELLKKSGQVVNLRL-----ERYLRGPKFEQLQQAIAANDKLPSSAPGTPSRAPMPTPVATT 441
            .:.|..::..|..|:|.:     :|:....:...|  ....|.:.|:|..|:.|.:.:
Human   391 EETVSRIQGQGSCVSLTVVDPEADRFFSMVRLSPL--LFLENTEAPASPRGSSSASLV------- 446

  Fly   442 SSATTTPSRSITRELEEEALPAPEAFMTTPPSVTTMTTTTLSSFGAGKQLVAVRDSLDGSTKIIP 506
              .|..||      ||:.::|:
Human   447 --ETEDPS------LEDTSVPS------------------------------------------- 460

  Fly   507 TEVVPLADKTEAKNSGVITRHKYYTDPELSDDAETEIIRKWQKIVGSDVEVIVAQIKKFAVGGLG 571
               |||..:          :...|..|.                                 |..|
Human   461 ---VPLGSR----------QCFLYPGPG---------------------------------GSYG 479

  Fly   572 ISLEGTVDVEGGREVRPHHYIRSILPDGPVGVNGVLRSGDELLEVNGERLLGMNHLEVVAILKEL 636
            ..|.   .|..|    |..:|..:.|.|.....| |:.||.:|||||..:.|.|.||   .|::|
Human   480 FRLS---CVASG----PRLFISQVTPGGSAARAG-LQVGDVILEVNGYPVGGQNDLE---RLQQL 533

  Fly   637 P 637
            |
Human   534 P 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Patj	NP_477342.1	L27	12..70	CDD:295425	10/64 (16%)
		PDZ_signaling	154..226	CDD:238492	20/71 (28%)
		PDZ_signaling	318..400	CDD:238492	23/89 (26%)
		PDZ_signaling	557..643	CDD:238492	25/81 (31%)
		PDZ_signaling	726..807	CDD:238492
PDZD3	XP_011541302.1	PDZ_signaling	113..193	CDD:238492	15/91 (16%)
		PDZ_signaling	221..298	CDD:238492	23/101 (23%)
		PDZ	326..411	CDD:214570	23/89 (26%)
		PDZ_signaling	466..545	CDD:238492	27/123 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810