DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patj and si:dkeyp-72e1.9

DIOPT Version :9

Sequence 1:	NP_477342.1	Gene:	Patj / 44100	FlyBaseID:	FBgn0067864	Length:	871	Species:	Drosophila melanogaster
Sequence 2:	XP_691844.3	Gene:	si:dkeyp-72e1.9 / 563388	ZFINID:	ZDB-GENE-120215-89	Length:	709	Species:	Danio rerio

Alignment Length:	766	Identity:	159/766 - (20%)
Similarity:	261/766 - (34%)	Gaps:	251/766 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 YATDYAQIQAIELVNDGTGLGFGIIG------ARNSGVIVKTILPGGVADKDGRLRSGDHILQIG 198
            |..|.| :.::|..:...|||..:||      ....||.||.|||||:|..||.|:.||.||::.
Zfish    29 YGVDRA-VHSMEFTDCENGLGIKVIGGVKELTGEEYGVYVKRILPGGLASSDGNLQPGDQILEVN 92

  Fly   199 DVNLHEMVSEQVAAVLR--QSGTHVRLVVARPVEQSVPTPQYALEPGTAVVPTRVLVDPAE-LER 260
            ..:|..:.||:...:||  .|..|:||::||..|......:...:.|:..........|.: ..|
Zfish    93 GESLIGVTSERAVDILRAASSTNHMRLLIARDEEARREFAELLEKYGSNGSTGSTRNSPIQHTGR 157

  Fly   261 YLISTGYPEIFGESSTASTPQTTTEDDRFVYRGETSMLIDP-----NID----LEELLALPETEK 316
            ||.||.    .|.||.:.:|                :|:.|     |.:    |...|:.|....
Zfish   158 YLDSTS----SGSSSRSQSP----------------LLLSPAGSQNNYNNTGPLLRSLSHPGEGV 202

  Fly   317 LQVELKKDANGLGITIAGYVCEKEELSGIFVKSVSPGSAADLSGRIRVNDRIIEVDGQSLQGYSN 381
            :|:.....:..|||||.| ...:.:...:|::.|..|......||:|..|::|.::.:||.|.:.
Zfish   203 IQLITVARSCSLGITIGG-GSNRPDGPAVFIQEVLSGGDCHRDGRLRPGDQLIAINKESLIGVTY 266

  Fly   382 HQAVELLKK----SGQVVNL------------------------------RLERYLRGPKFEQLQ 412
            .:|..:|.|    ...||::                              ||:.::|.|:..|.:
Zfish   267 EEAKSVLNKVKFSQDPVVDIAFIPGKGPFSSSPSLHNGVQRGVGNGYNSSRLKVHVRSPEMRQEE 331

  Fly   413 QA---IAANDKLPSSAPGTPSRAPMPTPVA----------------------------------- 439
            .|   .::.|..|.....:.|.|..|..|:
Zfish   332 TAPVLSSSPDICPPDIQVSASTAQRPATVSKPKISLDPHIRLKSEKLDLALSYLGLDVTDEKRRQ 396

  Fly   440 TTSSATTTP------------SRSITRELEEEALPAPEAFMTTPPSVTTMTTTTLSSFGAG---- 488
            ...|.||.|            :||:.:|..||.......||.:.....::..|  |:|.:.
Zfish   397 LRESLTTDPQGTVSYGDFVEATRSVYQEKLEEVGLGQGPFMFSYQEAASLMDT--SAFHSPTYES 459

  Fly   489 -----------------------KQLVAVRDSLDGSTKIIPTEVVPLADKTEAKNSGVITRHKYY 530
                                   |||..:....:.|.|.:..|:    .||..|.:..:..:|..
Zfish   460 ECSYSSEELEEFQNEVKHLQVQMKQLKVMLKDTEDSKKTLEDEL----QKTAEKATATLEENKCL 520

  Fly   531 TDPELSDDAETEIIRKWQKIVGSDVEVIVAQIKKFAVGGLGISLEGTVDVEGGREVRPHHYIRSI 595
            .    |.....|.:::.......|.|.:: |:.:..:..|...|.|.
Zfish   521 K----SKLQVAEAVQRQTNSAEQDYEEVI-QLLEAEIKDLKNQLAGK------------------ 562

  Fly   596 LPDGPVGVNGVLRSGDELLEVNGERL-----------LGMNHLEVVAILKELPLDVRMVCGRNRN 649
                  ...|:..:.::::::| .||           |...|||:                  .|
Zfish   563 ------NKRGLEATKEDVMDLN-RRLTAIDSQFRKSELTRKHLEI------------------SN 602

  Fly   650 SSLLPFSDDTLKKLSNNF----EN----LLPATDRLVKAKSDGSLATAGSVADGDSVAAAAASFS 706
            ..||.|:.:..|.|:|.:    ||    ..||||         |..|...:.|         |..
Zfish   603 KKLLGFAQNVHKVLTNTYLFGIENGSAQASPATD---------SPDTPSPIPD---------SAC 649

  Fly   707 KLKSRSLEPLTGLAMWSSQ----PQIIE--LVKGDRGLGFSILDYQDPLDP 751
            :|.:::.|.:.|:....::    ||.:|  :||.:....   .|.|.|..|
Zfish   650 QLAAKAKELVDGVCSLCTEDHTLPQYVEGSVVKAEEDCD---SDLQWPQPP 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patj	NP_477342.1	L27	12..70	CDD:295425
		PDZ_signaling	154..226	CDD:238492	31/79 (39%)
		PDZ_signaling	318..400	CDD:238492	24/115 (21%)
		PDZ_signaling	557..643	CDD:238492	12/96 (13%)
		PDZ_signaling	726..807	CDD:238492	9/28 (32%)
si:dkeyp-72e1.9	XP_691844.3	PDZ_signaling	42..122	CDD:238492	31/79 (39%)
		PDZ_signaling	203..273	CDD:238492	19/70 (27%)
		Prefoldin	471..590	CDD:238453	22/152 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19964
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010