Protein Alignment Patj and lnx1

DIOPT Version :10

• Sequence 1: NP_477342.1
• Gene: Patj / 44100
• FlyBaseID: FBgn0067864
• Length: 871
• Species: Drosophila melanogaster
• Sequence 2: XP_005160562.1
• Gene: lnx1 / 561226
• ZFINID: ZDB-GENE-030131-9439
• Length: 769
• Species: Danio rerio
• Alignment Length: 817
• Identity: 179/817 - (21%)
• Similarity: 274/817 - (33%)
• Gaps: 300/817 - (36%)

  Fly    57 DSLSELN--------------AQLAQHPSMLPNDFDIDVAGNLVLSLNGGEVMY----------- 96
            ||.|||.              |.|:..|.::...::..|..|   |.:|.....
Zfish   167 DSTSELTLAALPGEGCPSSAIALLSDEPGLVNPAYEPSVEDN---SQSGSTTSLAARSGSRKSEY 228

  Fly    97 -DFDEQRSSSHSHS--------APGSPDKSG-GVGEEPRPQSQNSKGAGV---ADLYATDYAQIQ 148
             :||  |:|..|.|        :.....||| .|..:...:..|.:.|.:   .:|:|..    |
Zfish   229 RNFD--RTSVRSRSFRRLNRAFSVLRRTKSGTAVANDTTEERDNLRNANIPAEGELFALP----Q 287

  Fly   149 AIELVNDG-------------TGLGFGIIGARNS---GVIVKTILPGGVADKDGRLRSGDHILQI 197
            ...|:.||             ..|...|:|...:   .::::.|...||..:||||..||.||::
Zfish   288 LHHLIPDGEVTSIKITRADPCEPLAISIVGGNETPLVRILIQDIYREGVIARDGRLLPGDMILKV 352

  Fly   198 GDVNLHEMVSEQVAAVLRQSGTHVRLVVARPVEQSVPTPQYALEPGTAVVPTRVLVDPAELERYL 262
            ..:::..:......|.|:|..|.:||.|.|.......:..::        ||
Zfish   353 NGIDISNVPHCYAVAALKQPCTLLRLTVLREQRHRYRSHHHS--------PT------------- 396

  Fly   263 ISTGYPEIFGESSTASTPQTTTEDDRFVYRGETSMLIDPNIDLEELLALPETEKLQVELKKDA-- 325
                      |:..|.|  .|..||                            .|.|.|.|.|
Zfish   397 ----------EAFPAHT--ATIRDD----------------------------SLHVVLVKRAPD 421

  Fly   326 NGLGITIAGYVCEKEELSGIFVKSVSPGSAADLSGRIRVNDRIIEVDGQSLQ-GYSNHQAVELLK 389
            ..|||.:.    .:.:..|:|:..:..|..|...||:||:||::.::|..|: |...|.|: |::
Zfish   422 EQLGIKLV----RRPDEHGVFIFHLLEGGLAARDGRLRVDDRVLAINGHDLRYGAPEHAAL-LIQ 481

  Fly   390 KSGQVVNLRLERYLRGPKFEQLQQAIAANDKLPSSAPGTPSRAPMPTPVATTSSATTTPSRSITR 454
            .|...|:..:.|....|..:.||:|       |.:..|.|..:|:
Zfish   482 ASEDRVHFIVSRQTHIPAPDILQEA-------PWNMEGPPPYSPV-------------------- 519

  Fly   455 ELEEEALPAPEAFMTTPPSVTTMTTTTLSSFGAGKQLVAVRDSLDGSTKIIPTEVVPLADKTEAK 519
            ::|...|.:.:     .|:....|.|.|..         ..||| |.|..
Zfish   520 DIEHTLLDSCQ-----KPACYEKTVTLLKE---------PHDSL-GMTVA--------------- 554

  Fly   520 NSGVITRHKYYTDPELSDDAETEIIRKWQKIVGSDVEVIVAQIKKFAVGGLGISLEGTVDVEGGR 584
             .|:.:|                         |.|:.|
Zfish   555 -GGMSSR-------------------------GWDLPV--------------------------- 566

  Fly   585 EVRPHHYIRSILPDGPVGVNGVLRSGDELLEVNGERLLGMNHLEVVAILKEL--PLDVRMVCGRN 647
                  |:.::.|:|.||..|.:|.||.||.|||..|.|:...|.||.||..  |:.::::..|.
Zfish   567 ------YVTNVDPNGVVGQEGSIRKGDILLNVNGVDLTGVTRSEAVANLKNTSSPVVLQVLEMRP 625

  Fly   648 RNSSLLPFSDDTLKKLSNNFENLLPATDRLVKAKSDGSLATAGSVADGDSVAAAAASFSKLKSRS 712
            .|.|.|    |.:..|.:      |.      |.|..|..........|..|
Zfish   626 PNESSL----DCMPPLHS------PC------ALSPSSPGDVKLPPPNDDYA------------- 661

  Fly   713 LEPLTGLAMWSSQPQI---------IELVKGDRG-LGFSILDYQDPLDPNDTLIVIRSLVPGGVA 767
              ||     |.|..|:         |.|.:...| |||||:..|:.|:.|.:.. |||:|.|..|
Zfish   662 --PL-----WVSWLQLPRHLYCCKDIVLRRSTSGSLGFSIVGGQEELNCNQSFF-IRSIVEGTPA 718

  Fly   768 QLDGRLIPGDRLLFVN---SINLENASLDQAVQALKG 801
            ..|||:..||.||.||   :..:.:.:|.:.::.|:|
Zfish   719 YNDGRIRCGDILLEVNGKSTWGMTHTALVRLLKELRG 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Patj	NP_477342.1	L27	12..70	CDD:470651	7/26 (27%)
		PDZ2_MUPP1-like	148..227	CDD:467155	25/94 (27%)
		PDZ3_MUPP1-like	315..401	CDD:467253	26/88 (30%)
		PDZ4_MUPP1-like	556..646	CDD:467156	23/91 (25%)
		PDZ5_MUPP1-like	719..816	CDD:467157	32/96 (33%)
lnx1	XP_005160562.1	mRING-HC-C3HC3D_LNX1	54..95	CDD:438435
		PDZ1_LNX1_2-like	295..383	CDD:467165	22/87 (25%)
		PDZ2_LNX1_2-like	411..493	CDD:467166	26/86 (30%)
		PDZ3_LNX1_2-like	537..622	CDD:467167	35/168 (21%)
		PDZ4_LNX1_2-like	678..766	CDD:467168	29/79 (37%)