DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patj and tamalin

DIOPT Version :9

Sequence 1:	NP_477342.1	Gene:	Patj / 44100	FlyBaseID:	FBgn0067864	Length:	871	Species:	Drosophila melanogaster
Sequence 2:	NP_001035013.1	Gene:	tamalin / 558950	ZFINID:	ZDB-GENE-060312-30	Length:	382	Species:	Danio rerio

Alignment Length:	240	Identity:	54/240 - (22%)
Similarity:	86/240 - (35%)	Gaps:	76/240 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   312 PETEKLQVEL-KKDANGLGITIAGYVCEKEELSGI----FVKSVSPGSAADLSGRIRVNDRIIEV 371
            ||.::..|.| ||:....|..|..|....:..:.:    ||..|...|.|.|:| ::|.|.|..|
Zfish    85 PEPQRKTVILEKKEEESFGFEIQTYGLHHQSENSVEMCTFVCKVHEDSPALLAG-LKVGDTIASV 148

  Fly   372 DGQSLQGYSNHQAVELLKKSGQVVNLRLE----------------RYLRGPKFEQ---------- 410
            :..|:.|:.:.:.|:|:|.||.  |:|||                :||:....|:
Zfish   149 NDTSVDGFRHKEIVQLIKSSGN--NIRLETVYSDSIRKAELEARLQYLKQTLHEKWDEYRSLMVQ 211

  Fly   411 --------LQQAIAANDKLPSSAPGTPSRAPMPTPVAT-----TSSATTTPSRSITRELEEEAL- 461
                    :...:|..:.|.|:  |.......|:|.|.     |.|.:::.|.......|::.|
Zfish   212 EQRLVHGIVMSDVAMYESLESA--GVYGSLGAPSPAALRALRGTDSTSSSVSHLSAATAEDDPLY 274

  Fly   462 --------------------------PAPEAFMTTPPSVTTMTTT 480
                                      ||.|.|.|...|:|...:|
Zfish   275 QTCIFNNTSNDQIHAKQENTRPRLIRPASELFTTAKTSLTRSAST 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patj	NP_477342.1	L27	12..70	CDD:295425
		PDZ_signaling	154..226	CDD:238492
		PDZ_signaling	318..400	CDD:238492	27/86 (31%)
		PDZ_signaling	557..643	CDD:238492
		PDZ_signaling	726..807	CDD:238492
tamalin	NP_001035013.1	PDZ_signaling	90..175	CDD:238492	27/87 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900