DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patj and Zasp66

DIOPT Version :9

Sequence 1:	NP_477342.1	Gene:	Patj / 44100	FlyBaseID:	FBgn0067864	Length:	871	Species:	Drosophila melanogaster
Sequence 2:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster

Alignment Length:	418	Identity:	89/418 - (21%)
Similarity:	150/418 - (35%)	Gaps:	114/418 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   167 RNSGVIVKTILPGGVADKDGRLRSGDHILQIGDVNLHEMVSEQVAAVLRQSGTHVRLVVARPVEQ 231
            :|.||.|     |..|  .|.|..||.|.:||:.:..::.......:.|.:|..:||||.|  :.
  Fly    64 QNVGVQV-----GSPA--HGELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHR--DN 119

  Fly   232 SVPTPQYALE---PGTA-----------VVPTR----VLVDPAELER-------YLISTGYPEI- 270
            .:...|.|.:   ||:.           ::|.|    .|..|:..||       .|..|.:|::
  Fly   120 KIAYTQGATQEAGPGSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPVDTLPQTVFPQLN 184

  Fly   271 ----FGESSTASTPQTTTEDDRFVYRGETSMLIDPNIDLEELLALPETEKLQVELKKDANGLGIT 331
                :...||..:|:.|.:..:.|...:.:::..|.....  |.||     ..::||||.    |
  Fly   185 SSGGYEVPSTVFSPKPTRDHQQDVDEEQAAIVNQPYRTTP--LVLP-----GAKVKKDAP----T 238

  Fly   332 IAGYV-------------------CEKEELSGIFVKSVSPGSAADLSGRI---RVNDRIIEVDGQ 374
            ...|:                   ..|:.::...:..| .||.|| :||:   :.|..|
  Fly   239 TESYLRHYPNPAVRAHPGHDYHDSIMKQRVADTMLHKV-VGSEAD-TGRVFHKQFNSPI------ 295

  Fly   375 SLQG-YSNHQAVELLKKSGQVVNLRLERYLRGPKFEQLQQAIAANDKLPSSAPGTPSRAPMPTPV 438
               | |||:...:.::.:                   :..|.:.:::|..|    |...|:||.:
  Fly   296 ---GLYSNNNIEDTIRST-------------------VPFATSESNRLKDS----PLHRPLPTKL 334

  Fly   439 -ATTSSATTTPSRSIT-RELEEEALPAPEAFMTTPPSVTTMTTTTLSSFGAGKQLVAVRDSLDGS 501
             ....:....|..|.| |.::||. .......::|..||....|.:..   ..:||..:..:...
  Fly   335 NGYKKTVQYDPRNSETYRAIQEEG-GYSNYGQSSPQEVTIPVQTKVYQ---PNRLVPGKKPVSAP 395

  Fly   502 TKIIPTEVVPLADKTEAKNSGVITRHKY 529
            ....|..||...|: ..:.||...|..|
  Fly   396 VSRPPYNVVNTHDE-NIRQSGSFNRLMY 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patj	NP_477342.1	L27	12..70	CDD:295425
		PDZ_signaling	154..226	CDD:238492	18/58 (31%)
		PDZ_signaling	318..400	CDD:238492	20/104 (19%)
		PDZ_signaling	557..643	CDD:238492
		PDZ_signaling	726..807	CDD:238492
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	15/53 (28%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558	20/106 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900