DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patj and Gopc

DIOPT Version :9

Sequence 1:	NP_477342.1	Gene:	Patj / 44100	FlyBaseID:	FBgn0067864	Length:	871	Species:	Drosophila melanogaster
Sequence 2:	NP_001101101.2	Gene:	Gopc / 309774	RGDID:	1309512	Length:	463	Species:	Rattus norvegicus

Alignment Length:	306	Identity:	72/306 - (23%)
Similarity:	120/306 - (39%)	Gaps:	64/306 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MHLSADISSALQ--QIEAVKKGIDESDDPKLQMQTAESLSTILGILQDPVFRTIVHVQDSLSELN 63
            :|...|:...|:  :.|.||:...|: :.||..:..|:|...:.:||..|:             .
  Rat   153 VHSMEDLERELEANKTEKVKEARLEA-EVKLLRKENEALRRHIAVLQAEVY-------------G 203

  Fly    64 AQLAQHPSMLPNDFDIDVAGNL-VLSLNGGEV---MYD--FDEQRSSSHSH-------SAPGSPD 115
            |:||      ....|.::||.: .:.|.|.::   .:|  :::..:..|.|       :..|..|
  Rat   204 ARLA------AKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRQD 262

  Fly   116 KSGGVGEEP-RPQSQNSKGAGVADLYATDYAQIQAIELVNDGTGLGFGIIGARNSGV--IVKTIL 177
            ....:...| ..|....|..||..:.       :.:.|..|..|||..|.|.:..||  ::..|.
  Rat   263 LKRPMQAPPGHDQDSLKKSQGVGPIR-------KVLLLKEDHEGLGISITGGKEHGVPILISEIH 320

  Fly   178 PGGVADKDGRLRSGDHILQIGDVNLHEMVSEQVAAVLRQSGTHVR---LVVARPVEQSVPTPQYA 239
            ||..||:.|.|..||.:|.:..|||.:...::...:|.|....:.   :.||..|:......:|.
  Rat   321 PGQPADRCGGLHVGDAVLAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYE 385

  Fly   240 LEPGTAVVPTRVLVDPAELERYLISTGYPEIFGESSTASTPQTTTE 285
            .|.|...   |:.:|  |||.           |.:|.||...::.|
  Rat   386 DESGHRY---RLYLD--ELEG-----------GGNSGASCKDSSGE 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patj	NP_477342.1	L27	12..70	CDD:295425	14/59 (24%)
		PDZ_signaling	154..226	CDD:238492	23/76 (30%)
		PDZ_signaling	318..400	CDD:238492
		PDZ_signaling	557..643	CDD:238492
		PDZ_signaling	726..807	CDD:238492
Gopc	NP_001101101.2	SMC_prok_B	<35..>215	CDD:274008	18/81 (22%)
Gopc	NP_001101101.2	PDZ_signaling	287..369	CDD:238492	24/88 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900