DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patj and Stxbp4

DIOPT Version :9

Sequence 1:	NP_477342.1	Gene:	Patj / 44100	FlyBaseID:	FBgn0067864	Length:	871	Species:	Drosophila melanogaster
Sequence 2:	XP_006247190.1	Gene:	Stxbp4 / 303443	RGDID:	1307903	Length:	557	Species:	Rattus norvegicus

Alignment Length:	166	Identity:	45/166 - (27%)
Similarity:	72/166 - (43%)	Gaps:	22/166 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   710 SRSLEPLTGLAMWSSQP--QIIELVKGDRGLGFSILDYQDPLDPND-TLIVIRSLVPGGVAQLDG 771
            :||..||      ...|  ::|.:.| :.|||..||   ..:|.|: .|:.|..:.|||....||
  Rat     8 ARSSSPL------ERDPAFRVITVAK-ETGLGLKIL---GGIDRNEGPLVYIHEVTPGGDCYKDG 62

  Fly   772 RLIPGDRLLFVNSINLENASLDQAVQALKGAS---KGVVRIGVAKPLPMTDNSLKACSNASTTSE 833
            ||.|||:|:.:|..::...|.::|...|..|.   :..:.|...:......:....|..:...||
  Rat    63 RLKPGDQLVSINKESMIGVSFEEAKNILTRAKLRWESPLEIAFIRQKSYCGHPGNICCQSPPVSE 127

  Fly   834 ETLDAQPSPPALPTVAPPA---MPPSASMGAEPDLI 866
               |.:|...|...::.||   :|.::|.....|.|
  Rat   128 ---DCEPQTSAFNLLSSPAGTLLPKTSSTPRTQDSI 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patj	NP_477342.1	L27	12..70	CDD:295425
		PDZ_signaling	154..226	CDD:238492
		PDZ_signaling	318..400	CDD:238492
		PDZ_signaling	557..643	CDD:238492
		PDZ_signaling	726..807	CDD:238492	28/86 (33%)
Stxbp4	XP_006247190.1	PDZ_signaling	21..94	CDD:238492	26/76 (34%)
		TPR_MLP1_2	299..400	CDD:285204
		GBP_C	<306..389	CDD:303769
		coiled coil	359..369	CDD:293879
		coiled coil	378..389	CDD:293879
		WW	502..531	CDD:278809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19964
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910