DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patj and Slc9a3r1

DIOPT Version :9

Sequence 1:	NP_477342.1	Gene:	Patj / 44100	FlyBaseID:	FBgn0067864	Length:	871	Species:	Drosophila melanogaster
Sequence 2:	NP_036160.1	Gene:	Slc9a3r1 / 26941	MGIID:	1349482	Length:	355	Species:	Mus musculus

Alignment Length:	366	Identity:	85/366 - (23%)
Similarity:	145/366 - (39%)	Gaps:	89/366 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 GLGFGIIGARNS-GVIVKTILPGGVADKDGRLRSGDHILQIGDVNLHEMVSEQVAAVLRQSGTHV 221
            |.||.:.|.:.. |..::.:.||..|:|.| |.:||.::::...|:.:...:||.:.:|.:...|
Mouse    23 GYGFHLHGEKGKVGQFIRLVEPGSPAEKSG-LLAGDRLVEVNGENVEKETHQQVVSRIRAALNAV 86

  Fly   222 RLVVARPVEQSVPTPQYALEPGTAVVPTRVLVDPAELERYLISTGYPEIFGESSTASTPQTTTED 286
            ||:|..|     .|.:...:.|.::  ...|:.|.|               :|..|..|..
Mouse    87 RLLVVDP-----ETDERLKKLGVSI--REELLRPQE---------------KSEQAEPPAA---- 125

  Fly   287 DRFVYRGETSMLIDPNIDLEELLALPETEKLQVE--------LKKDANGLGITIAGYVCEKEELS 343
                  .:|....|.|          |.||..:.        :||..||.|..:..   :|.: .
Mouse   126 ------ADTHEAGDQN----------EAEKSHLRELRPRLCTMKKGPNGYGFNLHS---DKSK-P 170

  Fly   344 GIFVKSVSPGSAADLSGRIRVNDRIIEVDGQSLQGYSNHQAVELLKKSGQ-----VVNLRLERYL 403
            |.|:::|.|.|.|:.|| :|..|||:||:|..::|..:...|..:|..|.     ||:...:.:.
Mouse   171 GQFIRAVDPDSPAEASG-LRAQDRIVEVNGVCMEGKQHGDVVSAIKGGGDEAKLLVVDKETDEFF 234

  Fly   404 RGPKFEQLQQAIAANDKLPSSAPGTPSRAPMPTPVATTSSATTTPSRSITRELEEEALPAPEAFM 468
            :..|      .|.:.:.|.         .|:|.|.:         :..|.:|...|||..|.:..
Mouse   235 KKCK------VIPSQEHLD---------GPLPEPFS---------NGEIQKESSREALVEPASES 275

  Fly   469 TTPP---SVTTMTTTTLSSFGAGKQLVAVRDSLDGSTKIIP 506
            ..|.   |.::.|:..|:|..:.|:.|:...|...|:...|
Mouse   276 PRPALARSASSDTSEELNSQDSPKRQVSTEPSSTSSSSSDP 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patj	NP_477342.1	L27	12..70	CDD:295425
		PDZ_signaling	154..226	CDD:238492	20/68 (29%)
		PDZ_signaling	318..400	CDD:238492	27/94 (29%)
		PDZ_signaling	557..643	CDD:238492
		PDZ_signaling	726..807	CDD:238492
Slc9a3r1	NP_036160.1	PDZ_signaling	12..91	CDD:238492	20/68 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	110..146		12/70 (17%)
		PDZ_signaling	147..226	CDD:238492	25/83 (30%)
		EBP50_C	230..355	CDD:286142	22/111 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	244..355		20/91 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900