DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patj and mics-1

DIOPT Version :9

Sequence 1:	NP_477342.1	Gene:	Patj / 44100	FlyBaseID:	FBgn0067864	Length:	871	Species:	Drosophila melanogaster
Sequence 2:	NP_001343863.1	Gene:	mics-1 / 179475	WormBaseID:	WBGene00011890	Length:	293	Species:	Caenorhabditis elegans

Alignment Length:	255	Identity:	53/255 - (20%)
Similarity:	99/255 - (38%)	Gaps:	45/255 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 VLVDPAELERYLISTGYPEIFGESSTASTPQTTTEDDRF--VYRGETS---MLIDPNIDLEELLA 310
            ::|.|.:.:....:...|.....::..|:|....||..|  .:..|.:   ...|...|.....:
Worm     1 MMVSPPQEDTVFNTDSDPVYEHHAALVSSPFHADEDHTFDISFAAEATDDMTFNDTTTDGNGQES 65

  Fly   311 LPETEKLQVELKKDANGLGITIAGYVCEKEELS--GIFVKSVSPGSAADLSGRIRVNDRIIEVDG 373
            :|......||::|.:.|.|..|.|.......:.  ||:|.||:  |.:...|.:|..|:|:..||
Worm    66 VPLEALTVVEIEKTSKGFGFNIVGGTDNPHFVGDIGIYVSSVN--SESKSYGVVRTGDKILSFDG 128

  Fly   374 QSLQGYSNHQAVELLK--KSGQVVNLRLERYLRGPKFEQLQQAIAANDKLPSSAPGTPSRAPMPT 436
            ..:...::.:|||:.:  |.|.|..:.::|     ::..||:                .|...||
Worm   129 IDMTYKTHDEAVEVFRSVKIGHVAKMLIDR-----EYLHLQE----------------DRTQTPT 172

  Fly   437 PVATTSSATTTPSRSITRELEEEALPAPEAFMTTPPSVT-TMTTTTLSSFGAGKQLVAVR 495
            ...:.:...|..:||.....:            ||.|:: :.:.:.|:|.|....:..:|
Worm   173 ASVSITPQVTPQTRSTQNNTD------------TPKSMSHSESKSRLTSHGLSAVIERIR 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patj	NP_477342.1	L27	12..70	CDD:295425
		PDZ_signaling	154..226	CDD:238492
		PDZ_signaling	318..400	CDD:238492	25/85 (29%)
		PDZ_signaling	557..643	CDD:238492
		PDZ_signaling	726..807	CDD:238492
mics-1	NP_001343863.1	PDZ_signaling	71..145	CDD:238492	22/75 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810